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Title:
NOVEL OXA-AND AZA-TRICYCLIC 4-PYRIDONE-3-CARBOXYLIC ACID FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
Document Type and Number:
WIPO Patent Application WO/2019/169539
Kind Code:
A1
Abstract:
Provided herein are oxa- and aza-tricyclic 4-pyridone-3-carboxylic acid compounds, their manufacture, pharmaceutical compositions comprising them, and their use as medicaments for inhibiting HBsAg secretion and HBV DNA production, and for treatment and/or prophylaxis of hepatitis B infection.

Inventors:
CHEN PING (CN)
ZHOU DING (CN)
CUI DAWEI (CN)
GAO XINGZHU (CN)
BAI YUANCHAO (CN)
Application Number:
CN2018/078063
Publication Date:
September 12, 2019
Filing Date:
March 05, 2018
Export Citation:
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Assignee:
PHARMARESOURCES SHANGHAI CO LTD (CN)
International Classes:
C07D471/04; A61K31/4985; A61K31/519; A61P31/20; C07D498/04
Domestic Patent References:
WO2018161960A12018-09-13
WO2018022282A12018-02-01
WO2017205115A12017-11-30
WO2015113990A12015-08-06
WO2017140821A12017-08-24
Foreign References:
CN107759585A2018-03-06
CN108727378A2018-11-02
Attorney, Agent or Firm:
SHANGHAI SHUONEE INTELLECTUAL PROPERTY LAW OFFICE (CN)
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