Title:
NOVEL OXA-AND AZA-TRICYCLIC 4-PYRIDONE-3-CARBOXYLIC ACID FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
Document Type and Number:
WIPO Patent Application WO/2019/169539
Kind Code:
A1
Abstract:
Provided herein are oxa- and aza-tricyclic 4-pyridone-3-carboxylic acid compounds, their manufacture, pharmaceutical compositions comprising them, and their use as medicaments for inhibiting HBsAg secretion and HBV DNA production, and for treatment and/or prophylaxis of hepatitis B infection.
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Inventors:
CHEN PING (CN)
ZHOU DING (CN)
CUI DAWEI (CN)
GAO XINGZHU (CN)
BAI YUANCHAO (CN)
ZHOU DING (CN)
CUI DAWEI (CN)
GAO XINGZHU (CN)
BAI YUANCHAO (CN)
Application Number:
PCT/CN2018/078063
Publication Date:
September 12, 2019
Filing Date:
March 05, 2018
Export Citation:
Assignee:
PHARMARESOURCES SHANGHAI CO LTD (CN)
International Classes:
A61K31/4985; C07D471/04; A61K31/519; A61P31/20; C07D498/04
Domestic Patent References:
| WO2018161960A1 | 2018-09-13 | |||
| WO2018022282A1 | 2018-02-01 | |||
| WO2017205115A1 | 2017-11-30 | |||
| WO2015113990A1 | 2015-08-06 | |||
| WO2017140821A1 | 2017-08-24 |
Foreign References:
| CN107759585A | 2018-03-06 | |||
| CN108727378A | 2018-11-02 |
Attorney, Agent or Firm:
SHANGHAI SHUONEE INTELLECTUAL PROPERTY LAW OFFICE (CN)
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