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Title:
NOVEL OXADIAZOLE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2011/001931
Kind Code:
A1
Abstract:
Provided is a novel compound that is useful as a therapeutic and/or preventative agent for neuropsychiatric disorders resulting from beta-amyloid. Said compound contains a compound represented by formula (I) or a pharmacologically permitted salt thereof. In formula (I), ring A represents an oxadiazole ring; ring B represents a benzene ring or pyridine ring and may be substituted; Q1, Q2, and Q3 each independently represent a hydrogen atom, a C1–6 alkoxy, or the like; ring C represents an imidazole ring, triazole ring, or the like, and may be substituted; X represents –R5, –NR5R6, –OR5, or the like; R3 and R4 each independently represent a hydrogen atom, a C1–6 alkyl, or the like; R5 represents an aryl, an aryl–C1–4 alkyl–, or the like, and may be substituted; R6 represents a hydrogen atom, a C1–6 alkyl, or the like; and n is an integer from 0 to 3.

Inventors:
IWAMA SEIJI (JP)
NAKAGAWA HIROSHI (JP)
KATO YOSHIHIRO (JP)
Application Number:
PCT/JP2010/060963
Publication Date:
January 06, 2011
Filing Date:
June 28, 2010
Export Citation:
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Assignee:
DAINIPPON SUMITOMO PHARMA CO (JP)
IWAMA SEIJI (JP)
NAKAGAWA HIROSHI (JP)
KATO YOSHIHIRO (JP)
International Classes:
C07D413/10; A61K31/4245; A61K31/4439; A61P25/28; A61P43/00; C07D413/14
Domestic Patent References:
WO2008042571A22008-04-10
WO2008156580A12008-12-24
WO2007074786A12007-07-05
Foreign References:
JP2007504282A2007-03-01
JP2009520751A2009-05-28
JP2008545007A2008-12-11
Attorney, Agent or Firm:
TANAKA, Mitsuo et al. (JP)
Mitsuo Tanaka (JP)
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