Title:
NOVEL PENTADIENOYL PIPERIDINE DERIVATIVE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/048005
Kind Code:
A3
Abstract:
The present invention relates to a novel pentadienoyl piperidine derivative, a pharmaceutical composition containing the same for preventing or treating a metabolic disease, and a functional food composition for alleviating or mitigating a metabolic disease using the same. The pentadienoyl piperidine derivative of the present invention inhibits the differentiation of preadipocytes, reduces body weight, visceral fat, blood lipid level, and blood sugar, improves a blood liver function index, and suppresses metabolic inflammation responses, and thus, ultimately, can be favorably used as a pharmaceutical composition or a functional food composition, which exhibits activity to prevent or treat a metabolic disease selected from the group consisting of obesity, diabetes, abnormal hypertriglyceridemia, fatty liver, and insulin resistance syndrome.
Inventors:
PARK TAE SUN (KR)
JEONG LAK SHIN (KR)
JEONG LAK SHIN (KR)
Application Number:
PCT/KR2015/009944
Publication Date:
August 18, 2016
Filing Date:
September 22, 2015
Export Citation:
Assignee:
INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIV (KR)
SNU R&DB FOUNDATION (KR)
SNU R&DB FOUNDATION (KR)
International Classes:
C07D211/32; A61K31/445; A61P3/04; C07D211/06
Domestic Patent References:
| WO2006068075A1 | 2006-06-29 | |||
| WO2005019177A1 | 2005-03-03 | |||
| WO2009004071A1 | 2009-01-08 |
Foreign References:
| US20070142394A1 | 2007-06-21 | |||
| US20040121994A1 | 2004-06-24 |
Attorney, Agent or Firm:
YANG, Boo Hyun (Chungdong Building 1922, Nambusunhwan-ro,Gwanak-gu, Seoul, KR)
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