Title:
NOVEL PEPTIDE FOR INHIBITING FAT ACCUMULATION, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OBESITY, COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2016/013897
Kind Code:
A1
Abstract:
The present invention relates to: a peptide for inhibiting fat accumulation, necessarily comprising an amino acid sequence represented by SEQ ID NO: 1; a pharmaceutical composition for preventing or treating obesity, comprising the same; and health functional food for preventing or improving obesity. The peptide for inhibiting fat accumulation according to the present invention has a function of inhibiting accumulation of fat tissues by inhibiting differentiation of mesenchymal stem cells into adipocytes, and therefore can be used widely in prevention or treatment of obesity.
Inventors:
CHUNG CHONG-PYOUNG (KR)
PARK YOON JEONG (KR)
LEE JUE-YEON (KR)
SUH JIN SOOK (KR)
JO IN HO (KR)
PARK YOON SHIN (KR)
PARK YOON JEONG (KR)
LEE JUE-YEON (KR)
SUH JIN SOOK (KR)
JO IN HO (KR)
PARK YOON SHIN (KR)
Application Number:
PCT/KR2015/007707
Publication Date:
January 28, 2016
Filing Date:
July 24, 2015
Export Citation:
Assignee:
UNIV SEOUL NAT R & DB FOUND (KR)
NANO INTELLIGENT BIOMED ENG (KR)
NANO INTELLIGENT BIOMED ENG (KR)
International Classes:
A61K38/08; A61K38/16; A61P3/00; A61P3/04
Foreign References:
| KR20130006194A | 2013-01-16 | |||
| KR100894265B1 | 2009-04-21 | |||
| KR100739528B1 | 2007-07-13 |
Other References:
CHOI, Y. J. ET AL.: "Determination of osteogenic or adipogenic lineages in muscle-derived stem cells (MDSCs) by a collagen-binding peptide (CBP) derived from bone sialoprotein (BSP).", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., vol. 419, 2012, pages 326 - 332, XP028466243, DOI: doi:10.1016/j.bbrc.2012.02.022
SHIN, M. K. ET AL.: "N-Formyl-Methionyl-Leucyl-Phenylalanine (fMLP) Promotes Osteoblast Differentiation via the N-Formyl Peptide Receptor 1-mediated Signaling Pathway in Human Mesenchymal Stem Cells from Bone Marrow.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 286, no. 19, 2011, pages 17133 - 17143, XP055289517
OTTO ET AL., CRIT REV BIOCHEM NOL BIOL., vol. 40, no. 4, 2005, pages 229 - 242
HIRSCH ET AL., CLIN ENDOCRINOL METAB., vol. 5, no. 2, 1976, pages 299 - 311
JOSEPH: "Price Remington, Remington's Pharmaceutical Science", MACK PUBLISHING COMPANY
See also references of EP 3189849A4
SHIN, M. K. ET AL.: "N-Formyl-Methionyl-Leucyl-Phenylalanine (fMLP) Promotes Osteoblast Differentiation via the N-Formyl Peptide Receptor 1-mediated Signaling Pathway in Human Mesenchymal Stem Cells from Bone Marrow.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 286, no. 19, 2011, pages 17133 - 17143, XP055289517
OTTO ET AL., CRIT REV BIOCHEM NOL BIOL., vol. 40, no. 4, 2005, pages 229 - 242
HIRSCH ET AL., CLIN ENDOCRINOL METAB., vol. 5, no. 2, 1976, pages 299 - 311
JOSEPH: "Price Remington, Remington's Pharmaceutical Science", MACK PUBLISHING COMPANY
See also references of EP 3189849A4
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
이처영 (KR)
이처영 (KR)
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