Title:
NOVEL PEPTIDE
Document Type and Number:
WIPO Patent Application WO/1995/008566
Kind Code:
A1
Abstract:
A peptide represented by general formula (I) or a pharmacologically acceptable salt thereof, wherein Q represents a physiologically active peptide residue; Xs represent the same or different 'alpha'-amino acid residues; M represents Gly or Cys; and m and n represent integers of, respectively, 5 to 8 and 0 to 3. The peptide ismore stable and/or active than straight-chain physiologically active peptides having no cyclic peptide linkage.
Inventors:
SHIBATA KENJI (JP)
SUZAWA TOSHIYUKI (JP)
YAMASAKI MOTOO (JP)
YAMADA KOJI (JP)
OGAWA TATSUHIRO (JP)
TANAKA TAKEO (JP)
SOGA SHIRO (JP)
SUZAWA TOSHIYUKI (JP)
YAMASAKI MOTOO (JP)
YAMADA KOJI (JP)
OGAWA TATSUHIRO (JP)
TANAKA TAKEO (JP)
SOGA SHIRO (JP)
Application Number:
PCT/JP1994/001554
Publication Date:
March 30, 1995
Filing Date:
September 21, 1994
Export Citation:
Assignee:
KYOWA HAKKO KOGYO KK (JP)
SHIBATA KENJI (JP)
SUZAWA TOSHIYUKI (JP)
YAMASAKI MOTOO (JP)
YAMADA KOJI (JP)
OGAWA TATSUHIRO (JP)
TANAKA TAKEO (JP)
SOGA SHIRO (JP)
SHIBATA KENJI (JP)
SUZAWA TOSHIYUKI (JP)
YAMASAKI MOTOO (JP)
YAMADA KOJI (JP)
OGAWA TATSUHIRO (JP)
TANAKA TAKEO (JP)
SOGA SHIRO (JP)
International Classes:
C07K7/56; C07K14/47; C07K14/58; C07K14/745; C07K16/40; A61K38/00; (IPC1-7): C07K7/56; C07K14/47; C07K14/58; C07K14/745; C07K16/40
Foreign References:
| JPH0395125A | 1991-04-19 | |||
| JPH03135997A | 1991-06-10 | |||
| JPH05262795A | 1993-10-12 | |||
| JPH03501610A | 1991-04-11 |
Other References:
The Journal of Antibiotics, Vol. 47, No. 3, (March 1994), YOSHIKAZU MORISHITA et al., "RES-701-1, a Novel and Selective Endothelin Type B Receptor Antagonist Produced by Streptomyces sp. RE-701", p. 269-275.
See also references of EP 0672680A4
See also references of EP 0672680A4
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