Title:
NOVEL PHARMACEUTICAL COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2016/114602
Kind Code:
A9
Abstract:
Disclosed herein a pharmaceutical composition comprising aprepitant or a pharmaceutically acceptable salt thereof; at least one hydrocarbon derivative selected from among a fatty acid of 14 to 18 carbon atoms, and a fatty alcohol of 14 to 18 carbon atoms; and at least one selected from among polyoxyethyelene-type nonionic surfactant, sucrose fatty acid ester, and Macrogol 15 hydroxystearate. The pharmaceutical composition of the present disclosure can release aprepitant or a pharmaceutically acceptable salt thereof to effectively exert the pharmaceutical efficacy, and can be dissolved in a fasted state simulated gastrointestinal fluid so that it can be useful for study on the in vivo pharmacokinetic behavior of aprepitant.
Inventors:
KIM SANGHEE (KR)
CHANG HEE CHUL (KR)
JUNG JI HOON (KR)
CHANG HEE CHUL (KR)
JUNG JI HOON (KR)
Application Number:
PCT/KR2016/000398
Publication Date:
October 06, 2016
Filing Date:
January 14, 2016
Export Citation:
Assignee:
DAE WOONG PHARMA (KR)
BIO-SYNECTICS INC (KR)
BIO-SYNECTICS INC (KR)
International Classes:
A61K31/5355; A61K9/20; A61K9/48; A61K31/045; A61P1/08; A61P25/00
Attorney, Agent or Firm:
YOU, Chi Youl et al. (Seokcheon-ro 397, Ojeong-gu, Bucheonsi, Gyeonggi-do 421-742, KR)
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