NOVEL PHENOLIC ACID DERIVATIVE COMPOUND AND USE THEREOF

WIPO Patent Application WO/2017/099531

A1

The present invention relates to a novel phenolic acid derivative compound having whitening and antioxidative activities and a use thereof and, more specifically, to a compound represented by chemical formula (1) below, an isomer thereof, or a salt thereof. The compounds according to the present invention can be favorably used not only for a pharmaceutical composition or cosmetic product for skin whitening due to skin whitening activity thereof through the inhibition of tyrosinase, but also for the prevention or improvement of skin aging and the like due to antioxidative activity thereof.

PARK JIN OH (KR)
LEE JI WON (KR)
LEE JAE YOUNG (KR)
LEE HYE JA (KR)
KWON BO KYUNG (KR)

PCT/KR2016/014470

June 15, 2017

December 09, 2016

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DAEBONG LS LTD (KR)

C07C233/64; A61K8/40; A61K8/44; A61K8/46; A61K31/166; A61Q19/02; A61Q19/08; C07C233/65; C07C327/16; C07C327/38

KR20110129516A	2011-12-02
KR20120053245A	2012-05-25
KR20140084032A	2014-07-04
KR101651605B1	2016-08-26

SAKAGUCHI: "Cell death-inducing activity by gallic acid derivatives", BIOL. PHARM. BULL., vol. 22, no. 5, 1999, pages 471 - 475, XP055599403
SILVIA, V.: "Novel molecular combination deriving from natural aminoacids and polyphenols: Design, synthesis and free-radical scavenging activities", EUR. J. MED. CHEM., vol. 50, 2012, pages 383 - 392, XP028471858, DOI: doi:10.1016/j.ejmech.2012.02.018

KOH, Bong Jin (KR)

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