NOVEL PHENYLPIPERAZINE ARYL UREA COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

WIPO Patent Application WO/2018/155954

A1

The present invention relates to a compound of a particular chemical formula or a pharmaceutically acceptable salt thereof and, more specifically, to a compound capable of preventing or treating Parkinson's disease, drug abuse, schizophrenia, or a bipolar disorder, by acting as an agonist for dopamine D3 receptor, or to a pharmaceutically acceptable salt thereof.

JPH10500938	[Title of the Invention] A sulfonamide derivative as an asparatil protease inhibitor
JP6253823	A carbamate compound, its manufacture, and use
JP2003508509	INDUSTRIAL APPLICABILITY: Amide as an inhibitor of pyruvate dehydrogenase

CHEON SEUNG HOON (KR)
KIM KYEONG MAN (KR)
CAO YONGKAI (KR)
SHIN CHAN YOUNG (KR)

PCT/KR2018/002256

August 30, 2018

February 23, 2018

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SHENZEN LINGLAN BIO PHARMACEUTICAL TECH CO LTD (CN)

C07D241/04; A61K31/155; A61K31/4725; A61K31/496

WO2004099179A1

2004-11-18

KR20070047763A	2007-05-07
JPH09278737A	1997-10-28
KR20170017792A	2017-02-15

DATABASE Chemical Abstract 30 April 2012 (2012-04-30), retrieved from STN Database accession no. 1371183-94-6
DATABASE Chemical Abstract 9 August 2016 (2016-08-09), retrieved from STN Database accession no. 899926-41-1
FLACHNER, B. ET AL.: "Rapid in Silico Selection of an MCHR1 Antagonists' Focused Library from Multi-million Compounds' Repositories: Biological Evaluation", MEDICINAL CHEMISTRY RESEARCH, vol. 23, no. 3, 2014, pages 1234 - 1247, XP055537088
CAPET, M. ET AL.: "Improving Selectivity of Dopamine D3 Receptor Ligands", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 26, no. 3, 2016, pages 885 - 888, XP029391922

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