Title:
NOVEL PHEROMONAL RECEPTOR OF SPODOPTERA LITTORALIS (LEPIDOPTERA, NOCTUIDAE) AND IDENTIFICATION OF NATURAL LIGAND OF SAID RECEPTOR AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2013/034666
Kind Code:
A3
Abstract:
The invention relates to the identification of Z9,E12-14:Ac as a natural ligand of the new olfactory/pheromonal receptor SlitOR6, a G-protein coupled-like receptor (GPCR-like). The invention encompasses the use of the interaction of SlitOR6 polypeptides and Z9,E12-14:Ac as the basis of screening assays for agents that modulate the activity of the SlitOR6 receptor. The invention also encompasses diagnostic and other assays performed based upon the SlitOR6/Z9,E12-14:Ac interaction, as well as kits for performing diagnostic and screening assays.
Inventors:
PATINY SEBASTIEN (BE)
JACQUIN-JOLY EMMANUELLE (FR)
MONTAGNE NICOLAS (FR)
JACQUIN-JOLY EMMANUELLE (FR)
MONTAGNE NICOLAS (FR)
Application Number:
PCT/EP2012/067467
Publication Date:
April 25, 2013
Filing Date:
September 07, 2012
Export Citation:
Assignee:
CHEMCOM SA (BE)
AGRONOMIQUE INST NAT RECH (FR)
UNIV PARIS CURIE (FR)
PATINY SEBASTIEN (BE)
JACQUIN-JOLY EMMANUELLE (FR)
MONTAGNE NICOLAS (FR)
AGRONOMIQUE INST NAT RECH (FR)
UNIV PARIS CURIE (FR)
PATINY SEBASTIEN (BE)
JACQUIN-JOLY EMMANUELLE (FR)
MONTAGNE NICOLAS (FR)
International Classes:
C07K14/705
Domestic Patent References:
| WO2006094704A2 | 2006-09-14 | |||
| WO2003016477A2 | 2003-02-27 | |||
| WO2008057561A2 | 2008-05-15 |
Other References:
JÜRGEN KRIEGER ET AL: "A divergent gene family encoding candidate olfactory receptors of the moth Heliothis virescens", EUROPEAN JOURNAL OF NEUROSCIENCE, OXFORD UNIVERSITY PRESS, GB, vol. 16, no. 4, 1 August 2002 (2002-08-01), pages 619 - 628, XP002676797, ISSN: 0953-816X, Retrieved from the Internet [retrieved on 20020919], DOI: 10.1046/J.1460-9568.2002.02109.X
DATABASE EMBL [online] 15 July 2010 (2010-07-15), "Spodoptera littoralis, EST, male antenna.", XP002676793, retrieved from EBI accession no. EM_EST:FQ020682 Database accession no. FQ020682
ISABELLE BRIGAUD ET AL: "Identification of an atypical insect olfactory receptor subtype highly conserved within noctuids", vol. 276, no. 22, 1 November 2009 (2009-11-01), pages 6537 - 6547, XP002676794, ISSN: 1742-464X, Retrieved from the Internet [retrieved on 20091005], DOI: 10.1111/J.1742-4658.2009.07351.X
KEHAT MOSHE ET AL: "Sex pheromones: Achievements in monitoring and mating disruption of cotton pests in Israel", ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY, vol. 22, no. 3-4, 1993, pages 425 - 431, XP002692435, ISSN: 0739-4462
DATABASE EMBL [online] 15 July 2010 (2010-07-15), "Spodoptera littoralis, EST, male antenna.", XP002676793, retrieved from EBI accession no. EM_EST:FQ020682 Database accession no. FQ020682
ISABELLE BRIGAUD ET AL: "Identification of an atypical insect olfactory receptor subtype highly conserved within noctuids", vol. 276, no. 22, 1 November 2009 (2009-11-01), pages 6537 - 6547, XP002676794, ISSN: 1742-464X, Retrieved from the Internet
KEHAT MOSHE ET AL: "Sex pheromones: Achievements in monitoring and mating disruption of cotton pests in Israel", ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY, vol. 22, no. 3-4, 1993, pages 425 - 431, XP002692435, ISSN: 0739-4462
Attorney, Agent or Firm:
VANHALST, Koen Victor Rachel et al. (E. Gevaertdreef 10a, Sint-Martens-Latem, BE)
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