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Patent Searching and Data


Title:
NOVEL PHOSPHOLIPASE D
Document Type and Number:
WIPO Patent Application WO2007089038
Kind Code:
A8
Abstract:
A modified phospholipase D having an ability to synthesize phosphatidylinositol which contains: (A) an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO:2 by substitution of at least one of the amino acid residues at the 187-, 191- and 385-positions by other amino acid residue(s); or (B) an amino acid sequence of a polypeptide derived from the amino acid sequence as described in the above (A) by substitution, deletion, insertion and/or addition of at least one amino acid residue at a position different from the 187-, 191- and 385-positions and having an ability to synthesize phosphatidylinositol. By using this modified phospholipase D, phosphatidylinositol can be efficiently produced from a phospholipid. It is also intended to provide a method of screening a phospholipase D having an ability to synthesize an acylglycerophospholipid having glycol group.

Inventors:
IWASAKI YUGO (JP)
NAKANO HIDEO (JP)
TAKAHASHI TETSUYA (JP)
Application Number:
PCT/JP2007/052172
Publication Date:
May 15, 2008
Filing Date:
February 01, 2007
Export Citation:
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Assignee:
UNIV NAGOYA (JP)
IWASAKI YUGO (JP)
NAKANO HIDEO (JP)
TAKAHASHI TETSUYA (JP)
International Classes:
C12N15/00; C12N9/16; C12N15/09; C12P9/00; C12Q1/34
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