Title:
NOVEL PHOSPHOLIPID PROCESSING AGENT
Document Type and Number:
WIPO Patent Application WO/2007/010892
Kind Code:
A1
Abstract:
[PROBLEMS] To provide a novel phospholipase B (PLB) having a poor hydrolytic activity on phosphatidylinositol (PI) among diacyl-phospholipids, and to provide a process for producing PI and glycerylphosphorylcholine (GPC) from a phospholipid mixture by exploiting the substrate specificity of the enzyme. [MEANS FOR SOLVING PROBLEMS] A phospholipid processing agent comprising an enzyme having such a PLB activity that is highly effective on a phospholipid other than PI (e.g., phosphatidylcholine (lecithin) and poorly effective on PI.
Inventors:
KOGA SHINJI (JP)
IMAMURA SHIGEYUKI (JP)
IMAMURA SHIGEYUKI (JP)
Application Number:
PCT/JP2006/314160
Publication Date:
January 25, 2007
Filing Date:
July 18, 2006
Export Citation:
Assignee:
ASAHI KASEI PHARMA CORP (JP)
KOGA SHINJI (JP)
IMAMURA SHIGEYUKI (JP)
KOGA SHINJI (JP)
IMAMURA SHIGEYUKI (JP)
International Classes:
C12N15/00; A23L1/30; A61K38/00; C12N9/16; C12N15/09; C12P9/00; C12P19/44
Foreign References:
| JPH0387191A | 1991-04-11 | |||
| JPS63105685A | 1988-05-10 | |||
| JPS63157993A | 1988-06-30 | |||
| JP2004532857A | 2004-10-28 | |||
| JP2005058017A | 2005-03-10 | |||
| JPH08169891A | 1996-07-02 |
Other References:
LONGHI S. ET AL.: "Cloning and nucleotide sequences of two lipase genes from Candida cylindracea", BIOCHIM. BIOPHYS. ACTA, vol. 1131, no. 2, 1992, pages 227 - 232, XP009005513
LOTTI M. ET AL.: "Cloning and analysis of Candida cylindracea lipase sequences", GENE, vol. 124, no. 1, 1993, pages 45 - 55, XP001084201
See also references of EP 1918371A4
LOTTI M. ET AL.: "Cloning and analysis of Candida cylindracea lipase sequences", GENE, vol. 124, no. 1, 1993, pages 45 - 55, XP001084201
See also references of EP 1918371A4
Attorney, Agent or Firm:
ISHII, Yoshio et al. (4F. 7-7, Toranomon 2-chome, Minato-k, Tokyo 01, JP)
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