Title:
NOVEL POLYENE-SPECIFIC GLYCOSYLTRANSFERASE DERIVED FROM PSEUDONOCARDIA AUTOTROPHICA
Document Type and Number:
WIPO Patent Application WO/2015/064998
Kind Code:
A1
Abstract:
The present invention relates to a novel polyene-specific glycosyltransferase derived from Pseudonocardia autotrophica, and provides glycosyltransferase comprising an amino acid sequence of SEQ ID NO: 1 and a gene encoding the glycosyltransferase. In addition, the present invention provides a recombinant expression vector comprising the gene and a recombinant microorganism transformed with the recombinant expression vector. In addition, the present invention provides a method for producing glycosyltransferase, comprising the steps of: culturing transgenic recombinant microorganisms; and isolating glycosyltransferase from the cultured recombinant microorganisms.
Inventors:
KIM EUNG SOO (KR)
LEE MI JIN (KR)
KIM HYE JIN (KR)
LEE MI JIN (KR)
KIM HYE JIN (KR)
Application Number:
PCT/KR2014/010161
Publication Date:
May 07, 2015
Filing Date:
October 28, 2014
Export Citation:
Assignee:
INHA IND PARTNERSHIP INST (KR)
International Classes:
C12N9/10; C12N1/21; C12N15/54
Domestic Patent References:
| WO2013100315A1 | 2013-07-04 |
Foreign References:
| KR20100089370A | 2010-08-12 |
Other References:
KIM, YONG-GEONG ET AL.: "Investigation of the NPP-specific polyene glycosyltransferase from Pseudonocardia autotrophica", KSBE, 2013 FALL CONFERENCE AND INTERNATIONAL SYMPOSIUM, 16 October 2013 (2013-10-16), pages 218
LEE, MI-JIN ET AL.: "Structural analysis and biosynthetic engineering of a solubility-improved and less-hemolytic nystatin-like polyene in Pseudonocardia autotrophica", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 95, no. 1, 1 March 2012 (2012-03-01), pages 157 - 168
DATABASE GENBANK 27 May 2013 (2013-05-27), accession no. GM12656.1
LEE, MI-JIN ET AL.: "Structural analysis and biosynthetic engineering of a solubility-improved and less-hemolytic nystatin-like polyene in Pseudonocardia autotrophica", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 95, no. 1, 1 March 2012 (2012-03-01), pages 157 - 168
DATABASE GENBANK 27 May 2013 (2013-05-27), accession no. GM12656.1
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)
특허법인 태백 (KR)
특허법인 태백 (KR)
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