Title:
NOVEL POLY(ETHYLENE GLYCOL) DERIVATIVE AND PROTEIN-ADSORPTION INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2019/049734
Kind Code:
A1
Abstract:
Provided is a compound which has an extremely high protein-adsorption inhibition effect wherein the compound is effectively adsorbed onto the surface of a base, e.g., an immunoreaction vessel, to prevent non-specific adsorption of proteins, etc., and which has such excellent cleaning resistance that said effect does not change through cleaning of the base. Also provided are a protein-adsorption inhibitor including said compound, a phosphorylcholine-modified base, and a method for inhibiting protein adsorption. The compound is a phosphorylcholine-group-containing poly(ethylene glycol) derivative represented by formula (1). The method for inhibiting protein adsorption according to the present invention includes a step in which an adsorption layer of the derivative is formed on a base surface.
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Inventors:
KATORI AKANE (JP)
MATSUDA MASARU (JP)
NODA TOMOZUMI (JP)
SASAKI TAKASHI (JP)
SUZUKI HIROTAKA (JP)
SAKAMOTO NOBUYUKI (JP)
MATSUDA MASARU (JP)
NODA TOMOZUMI (JP)
SASAKI TAKASHI (JP)
SUZUKI HIROTAKA (JP)
SAKAMOTO NOBUYUKI (JP)
Application Number:
PCT/JP2018/031801
Publication Date:
March 14, 2019
Filing Date:
August 28, 2018
Export Citation:
Assignee:
NOF CORP (JP)
International Classes:
C08G65/32; G01N33/531
Domestic Patent References:
| WO2012086762A1 | 2012-06-28 | |||
| WO2012086762A1 | 2012-06-28 |
Foreign References:
| CN102070780A | 2011-05-25 | |||
| CN106589290A | 2017-04-26 | |||
| JP2015117269A | 2015-06-25 | |||
| JPH0783923A | 1995-03-31 | |||
| JPH0783923A | 1995-03-31 | |||
| JP2015117269A | 2015-06-25 |
Other References:
See also references of EP 3683252A4
Attorney, Agent or Firm:
SAKAI Hajime et al. (JP)
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