Title:
NOVEL POLYMER-BASED HYDROTROPES FOR HYDROPHOBIC DRUG DELIVERY
Document Type and Number:
WIPO Patent Application WO/2015/155810
Kind Code:
A1
Abstract:
The invention disclosed herein relates to a polymer conjugate characterized in that the backbone of the polymer is an anionic polymer and hydrophobic moieties are covalently attached to the backbone of the polymer, a polymer micelle derived from the polymer conjugate, a composition comprising the polymer micelle, and a method for treating a disease or condition using thereof.
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Inventors:
YING WENBIN (US)
TSANG KWOK YIN (US)
BAI HAO (US)
YIN HAIQING (US)
LIU JIHUA (US)
WANG LI (US)
TSANG KWOK YIN (US)
BAI HAO (US)
YIN HAIQING (US)
LIU JIHUA (US)
WANG LI (US)
Application Number:
PCT/JP2014/004480
Publication Date:
October 15, 2015
Filing Date:
September 01, 2014
Export Citation:
Assignee:
NITTO DENKO CORP (JP)
International Classes:
C08G69/10; A61K47/48; C08G69/48; C09K23/52
Domestic Patent References:
| WO2007067417A1 | 2007-06-14 | |||
| WO2013154707A1 | 2013-10-17 | |||
| WO2010014117A1 | 2010-02-04 | |||
| WO2007067417A1 | 2007-06-14 | |||
| WO2010014117A1 | 2010-02-04 |
Foreign References:
| US20070160568A1 | 2007-07-12 | |||
| US20070010652A1 | 2007-01-11 |
Other References:
JI YOUNG KIM ET AL: "Hydrotropic polymer micelles as versatile vehicles for delivery of poorly water-soluble drugs", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, vol. 152, no. 1, 11 February 2011 (2011-02-11), pages 13 - 20, XP028226319, ISSN: 0168-3659, [retrieved on 20110223], DOI: 10.1016/J.JCONREL.2011.02.014
KINAM ET AL., PHARMACEUTICAL RESEARCH, vol. 20, 2003, pages 1022 - 1030
KINAM ET AL., JOURNAL OF CONTROLLED RELEASE, vol. 152, 2011, pages 13 - 20
BAEK ET AL., J. BIOMATER. SCI. POLYMER EDN, vol. 15, no. 4, 2004, pages 527 - 542
SANG VAN ET AL., INT J NANOMEDICINE, vol. 5, 2010, pages 825 - 837
XU ET AL., ADV DRUG DELIV REV., vol. 65, no. 1, 2013, pages 121 - 38
YU ET AL., MOL MEMBR BIOL., vol. 27, no. 7, 2010, pages 286 - 98
KAMALY ET AL., CHEM SOC REV., vol. 41, no. 7, 2012, pages 2971 - 3010
"Remington's Pharmaceutical Sciences", 1990, MACK PUBLISHING CO.
FINGL ET AL., THE PHARMACOLOGICAL BASIS OF THERAPEUTICS, 1975
KINAM ET AL., PHARMACEUTICAL RESEARCH, vol. 20, 2003, pages 1022 - 1030
KINAM ET AL., JOURNAL OF CONTROLLED RELEASE, vol. 152, 2011, pages 13 - 20
BAEK ET AL., J. BIOMATER. SCI. POLYMER EDN, vol. 15, no. 4, 2004, pages 527 - 542
SANG VAN ET AL., INT J NANOMEDICINE, vol. 5, 2010, pages 825 - 837
XU ET AL., ADV DRUG DELIV REV., vol. 65, no. 1, 2013, pages 121 - 38
YU ET AL., MOL MEMBR BIOL., vol. 27, no. 7, 2010, pages 286 - 98
KAMALY ET AL., CHEM SOC REV., vol. 41, no. 7, 2012, pages 2971 - 3010
"Remington's Pharmaceutical Sciences", 1990, MACK PUBLISHING CO.
FINGL ET AL., THE PHARMACOLOGICAL BASIS OF THERAPEUTICS, 1975
Attorney, Agent or Firm:
MITSUHASHI, Motoki et al. (KUZUWA & PARTNERS Nishi-Shinjuku Mitsui Bldg. 17F, 6-24-1, Nishi-Shinjuku, Shinjuku-k, Tokyo 23, JP)
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