Title:
NOVEL POLYMORPHIC FORMS OF AN ANTIDIABETIC AGENT: PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM
Document Type and Number:
WIPO Patent Application WO2000063193
Kind Code:
A9
Abstract:
This invention relates to novel polymorphic/pseudopolymorphic forms of arginine salt of 3-[4-[2-(phenoxazin-10-yl)ethoxy]phenyl]-2-ethoxypropanoic acid, having formula (I). The invention also relates to a pharmaceutical composition comprising the novel polymorphic form or their mixture and a pharmaceutically acceptable carrier. The polymorphic forms of the present invention are more active, as antidiabetic and hypolipidemic agent, than the novel 3-[4-[2-(phenoxazin-10-yl)ethoxy]phenyl]-2-ethoxypropanoic acid.
Inventors:
GADDAM OM REDDY (IN)
POTLAPALLY RAJENDRA KUMAR (IN)
SIRISILLA RAJU (IN)
KRISHNAMURTHY VYAS (IN)
DHARMARAJA SREENIVASA RAO (IN)
MAMAILLAPALLY RAMABHADRA SARMA (IN)
EBDRUP SOEREN (DK)
LUGSTEIN PETRA CHRISTINE (AT)
POTLAPALLY RAJENDRA KUMAR (IN)
SIRISILLA RAJU (IN)
KRISHNAMURTHY VYAS (IN)
DHARMARAJA SREENIVASA RAO (IN)
MAMAILLAPALLY RAMABHADRA SARMA (IN)
EBDRUP SOEREN (DK)
LUGSTEIN PETRA CHRISTINE (AT)
Application Number:
PCT/US2000/010309
Publication Date:
April 04, 2002
Filing Date:
April 17, 2000
Export Citation:
Assignee:
REDDY RESEARCH FOUNDATION (IN)
REDDY CHEMINOR INC (US)
GADDAM OM REDDY (IN)
POTLAPALLY RAJENDRA KUMAR (IN)
SIRISILLA RAJU (IN)
KRISHNAMURTHY VYAS (IN)
DHARMARAJA SREENIVASA RAO (IN)
MAMAILLAPALLY RAMABHADRA SARMA (IN)
EBDRUP SOEREN (DK)
LUGSTEIN PETRA CHRISTINE (AT)
REDDY CHEMINOR INC (US)
GADDAM OM REDDY (IN)
POTLAPALLY RAJENDRA KUMAR (IN)
SIRISILLA RAJU (IN)
KRISHNAMURTHY VYAS (IN)
DHARMARAJA SREENIVASA RAO (IN)
MAMAILLAPALLY RAMABHADRA SARMA (IN)
EBDRUP SOEREN (DK)
LUGSTEIN PETRA CHRISTINE (AT)
International Classes:
A61K31/538; A61P3/04; A61P3/10; C07C279/14; C07D265/38; (IPC1-7): C07D265/38; A61K31/535
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