Title:
NOVEL POLYMORPHS OF ATOVAQUONE AND PROCESS OF PREPARATION THEREOF
Document Type and Number:
WIPO Patent Application WO2006008752
Kind Code:
A8
Abstract:
Novel crystalline forms of anti Pneumocystis carinii compound (2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone) commonly known as Atovaquone and methods for producing the same is disclosed herein. This also provides pharmaceutical compositions comprising the said polymorphs of Atovaquone and method of treating Pneumocystis carinii pneumonia, the method comprising administering to a warm blooded animal an effective amount of a product-by-process composition of matter comprising polymorphic forms of Atovaquone.
Inventors:
TARUR VENKATASUBRAMANIAN RADHA (IN)
SATHE DHANANJAY GOVIND (IN)
MANTRIPRAGADA NARAYANA RAO (IN)
SAWANT KAMLESH DIGAMBAR (IN)
PATEL GAUTAM RAMJIBHAI (IN)
SATHE DHANANJAY GOVIND (IN)
MANTRIPRAGADA NARAYANA RAO (IN)
SAWANT KAMLESH DIGAMBAR (IN)
PATEL GAUTAM RAMJIBHAI (IN)
Application Number:
PCT/IN2004/000213
Publication Date:
June 15, 2006
Filing Date:
July 16, 2004
Export Citation:
Assignee:
USV LTD (IN)
TARUR VENKATASUBRAMANIAN RADHA (IN)
SATHE DHANANJAY GOVIND (IN)
MANTRIPRAGADA NARAYANA RAO (IN)
SAWANT KAMLESH DIGAMBAR (IN)
PATEL GAUTAM RAMJIBHAI (IN)
TARUR VENKATASUBRAMANIAN RADHA (IN)
SATHE DHANANJAY GOVIND (IN)
MANTRIPRAGADA NARAYANA RAO (IN)
SAWANT KAMLESH DIGAMBAR (IN)
PATEL GAUTAM RAMJIBHAI (IN)
International Classes:
C07C46/10; C07C50/32
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