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Patent Searching and Data


Title:
NOVEL POLYPEPTIDE, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2014/208583
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a new means for inducing, in a host, efficient secretory production of a target protein. The present invention relates to: a novel polypeptide exhibiting activity with which secretion productivity of a target protein is improved; a gene including a base sequence encoding said polypeptide; a vector including said gene; a transformant obtained by using said vector to transform a host cell; and a protein production method including a step in which said transformant is cultured, and the target protein is recovered from a culture product.

Inventors:
NISHI TERUYUKI (JP)
ASAI KIYOSHI (JP)
HAGIWARA HIROKO (JP)
MACHIDA MASAYUKI (JP)
Application Number:
PCT/JP2014/066805
Publication Date:
December 31, 2014
Filing Date:
June 25, 2014
Export Citation:
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Assignee:
KANEKA CORP (JP)
NAT INST OF ADVANCED IND SCIEN (JP)
International Classes:
C12N15/09; C07K14/39; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/11; C12P21/02
Domestic Patent References:
WO2012102171A12012-08-02
WO2011046218A12011-04-21
Foreign References:
JP2009082033A2009-04-23
Other References:
DATABASE GENBANK [online] 22 July 2009 (2009-07-22), "KOMAGATAELLA PHAFFII GS115 TRANSCRIPTIONAL REGULATORY PROTEIN PARTIAL MRNA", XP055308040, retrieved from NCBI Database accession no. XM_002490485
SOUCIET J. ET AL: "Genomic exploration of the hemiascomycetous yeasts: 1. A set of yeast species for molecular evolution studies", FEBS LETTERS, vol. 487, no. 1, 2000, pages 3 - 12, XP004337869
DATABASE GENBANK [online] RAVIN N.V. ET AL: "Definition: Ogataea parapolymorpha DL-1 chr5, whole genome shotgun sequence", XP055307231, retrieved from NCBI Database accession no. AEOI02000008
RAVIN N.V. ET AL: "Genome sequence and analysis of methylotrophic yeast Hansenula polymorpha DL1", BMC GENOMICS, vol. 14, no. 837, 27 November 2013 (2013-11-27), pages 1 - 20, XP021170655
APPL. MICROBIOL. BIOTECHNOL., vol. 54, no. 6, December 2000 (2000-12-01), pages 741 - 50
J. BIOCHEM., vol. 134, no. 6, December 2003 (2003-12-01), pages 813 - 7
PLOS ONE, vol. 5, 2010, pages EL 4404
"Molecular Cloning", 1989, COLD SPRING HARBOR LABORATORY PRESS
"Current Protocols in Molecular Biology", GREENE PUBLISHING ASSOCIATES AND WILEY-INTERSCIENCE
See also references of EP 3015548A4
Attorney, Agent or Firm:
HIRAKI Yusuke et al. (JP)
Yusuke Hiraki (JP)
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