Title:
NOVEL POLYPEPTIDE
Document Type and Number:
WIPO Patent Application WO/2023/040963
Kind Code:
A1
Abstract:
The present disclosure provides a novel polypeptide. Also provided is an ophthalmic composition for treating or preventing dry eye (DE) or DE associated disorders. Also provided is a method for treating or preventing DE or DE associated disorders, stimulating tears, stabilizing tear film or any combination thereof in a subject in need thereof, comprising administering to the subject an effective amount of the novel peptides. Also provided is a contact lenses care product comprising the novel peptides and the preparation method thereof.
Inventors:
ZHANG YINGHAO (CN)
YAN GUIRUI (CN)
WANG YAO (CN)
LI WENHAN (CN)
YAN GUIRUI (CN)
WANG YAO (CN)
LI WENHAN (CN)
Application Number:
PCT/CN2022/119040
Publication Date:
March 23, 2023
Filing Date:
September 15, 2022
Export Citation:
Assignee:
SHANGHAI PUYOU BIOCHEMICAL CO LTD (CN)
International Classes:
C07K14/47; A61K38/17; A61K45/00; A61K48/00; A61P27/02; C07K19/00
Foreign References:
| US20190085041A1 | 2019-03-21 | |||
| CN110302362A | 2019-10-08 | |||
| CN113150105A | 2021-07-23 | |||
| CN111770988A | 2020-10-13 |
Other References:
ZHANG YINGHAO; CHANG FANG-MEI; HUANG JIANJUN; JUNCO JACOB J.; MAFFI SHIVANI K.; PRIDGEN HANNAH I.; CATANO GABRIEL; DANG HONG; DING: "DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells", PROTEIN & CELL, SPRINGER ASIA, BEIJING, CN, vol. 5, no. 2, 11 February 2014 (2014-02-11), Beijing, CN , pages 124 - 140, XP035734439, ISSN: 1674-800X, DOI: 10.1007/s13238-013-0018-8
GONG，C.X.: "DSSylation， a novel guide for protein degradation", PROTEIN CELL, vol. 5, no. 2, 31 December 2014 (2014-12-31), pages 91 - 93, XP035734440, DOI: 10.1007/s13238-014-0020-9
GONG，C.X.: "DSSylation， a novel guide for protein degradation", PROTEIN CELL, vol. 5, no. 2, 31 December 2014 (2014-12-31), pages 91 - 93, XP035734440, DOI: 10.1007/s13238-014-0020-9
Attorney, Agent or Firm:
AFD CHINA INTELLECTUAL PROPERTY LAW OFFICE (CN)
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