Title:
NOVEL PROPHYLACTIC OR THERAPEUTIC AGENT FOR NOVEL CORONAVIRUS INFECTION-RELATED DISEASE
Document Type and Number:
WIPO Patent Application WO/2023/022198
Kind Code:
A1
Abstract:
A prophylactic or therapeutic agent for a novel coronavirus infection (COVID-19)-related disease, said agent comprising a cephem compound and/or a quinolone antimicrobial agent as an active ingredient.
Inventors:
NOGUCHI TAKUYA (JP)
MATSUZAWA ATSUSHI (JP)
MATSUZAWA ATSUSHI (JP)
Application Number:
PCT/JP2022/031225
Publication Date:
February 23, 2023
Filing Date:
August 18, 2022
Export Citation:
Assignee:
UNIV TOHOKU (JP)
International Classes:
A61K31/546; A61K31/5365; A61K31/5383; A61K31/545; A61P7/02; A61P11/00; A61P31/04; A61P37/06; A61P43/00; C12N5/078; C12N7/06
Domestic Patent References:
| WO2021177332A1 | 2021-09-10 |
Foreign References:
| CN111544540A | 2020-08-18 | |||
| CN111265616A | 2020-06-12 | |||
| JP2015044825A | 2015-03-12 |
Other References:
DUROJAIYE ASHIMIYU B., CLARKE JOHN-ROSS D., STAMATIADES GEORGE A., WANG CAN: "Repurposing cefuroxime for treatment of COVID-19: a scoping review of in silico studies", JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ADENINE PRESS, NEW YORK, NY, US, vol. 39, no. 12, 13 August 2021 (2021-08-13), US , pages 4547 - 4554, XP093036607, ISSN: 0739-1102, DOI: 10.1080/07391102.2020.1777904
NAGAMANI M.; VISHNU T.; JALAPATHI P.; SRINIVAS M.: "Molecular docking studies on COVID-19 and antibacterial evaluation of newly synthesized 4-(methoxymethyl)-1,2,3-triazolean analogues derived from (E)-1-phenyl-3-(2-(piperidin-1-yl)quinolin-3-yl) prop-2-en-1-one", IRANIAN CHEMICAL SOCIETY. JOURNAL, IRANIAN CHEMICAL SOCIETY, IR, vol. 19, no. 4, 17 August 2021 (2021-08-17), IR , pages 1049 - 1060, XP037718698, ISSN: 1735-207X, DOI: 10.1007/s13738-021-02365-y
LOPEZ ALEXANDRE; LAKBAR INES; DELAMARRE LOUIS; CULVER AURéLIEN; ARBELOT CHARLOTTE; DUCLOS GARY; HAMMAD EMMANUELLE; PASTENE BR: "Management of SARS-CoV-2 pneumonia in intensive care unit: An observational retrospective study comparing two bundles", JOURNAL OF CRITICAL CARE, GRUNE AND STRATTON, ORLANDO, FL, US, vol. 65, 29 June 2021 (2021-06-29), US , pages 200 - 204, XP086806879, ISSN: 0883-9441, DOI: 10.1016/j.jcrc.2021.06.014
YAKAME KEN, SHOJI TAKAYO, KANAZAWA TAKAMORI, SATO MITSUNORI, KAWASAKI TATSUYA: "Severe neonatal COVID‐19 pneumonia requiring mechanical ventilation", PEDIATRICS INTERNATIONAL, JAPAN PEDIATRIC SOCIETY, HOBOKEN, USA, vol. 64, no. 1, 1 January 2022 (2022-01-01), Hoboken, USA, XP093036612, ISSN: 1328-8067, DOI: 10.1111/ped.14677
BAVARO DAVIDE FIORE, BELATI ALESSANDRA, DIELLA LUCIA, STUFANO MONICA, ROMANELLI FEDERICA, SCALONE LUCA, STOLFA STEFANIA, RONGA LUI: "Cefiderocol-Based Combination Therapy for “Difficult-to-Treat” Gram-Negative Severe Infections: Real-Life Case Series and Future Perspectives", ANTIBIOTICS, vol. 10, no. 6, pages 652, XP093036614, DOI: 10.3390/antibiotics10060652
KHAN ANIS A., SLIFER TERI R., REMINGTON JACK S.: "Effect of Trovafloxacin on Production of Cytokines by Human Monocytes", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 42, no. 7, 1 July 1998 (1998-07-01), US , pages 1713 - 1717, XP093036616, ISSN: 0066-4804, DOI: 10.1128/AAC.42.7.1713
ALIREZA PANIRI, AKHAVAN-NIAKI HALEH: "Emerging role of IL-6 and NLRP3 inflammasome as potential therapeutic targets to combat COVID-19: Role of lncRNAs in cytokine storm modulation", LIFE SCIENCE, PERGAMON PRESS, OXFORD, GB, vol. 257, 18 July 2020 (2020-07-18), GB , pages 118114, XP055724892, ISSN: 0024-3205, DOI: 10.1016/j.lfs.2020.118114
NAGAMANI M.; VISHNU T.; JALAPATHI P.; SRINIVAS M.: "Molecular docking studies on COVID-19 and antibacterial evaluation of newly synthesized 4-(methoxymethyl)-1,2,3-triazolean analogues derived from (E)-1-phenyl-3-(2-(piperidin-1-yl)quinolin-3-yl) prop-2-en-1-one", IRANIAN CHEMICAL SOCIETY. JOURNAL, IRANIAN CHEMICAL SOCIETY, IR, vol. 19, no. 4, 17 August 2021 (2021-08-17), IR , pages 1049 - 1060, XP037718698, ISSN: 1735-207X, DOI: 10.1007/s13738-021-02365-y
LOPEZ ALEXANDRE; LAKBAR INES; DELAMARRE LOUIS; CULVER AURéLIEN; ARBELOT CHARLOTTE; DUCLOS GARY; HAMMAD EMMANUELLE; PASTENE BR: "Management of SARS-CoV-2 pneumonia in intensive care unit: An observational retrospective study comparing two bundles", JOURNAL OF CRITICAL CARE, GRUNE AND STRATTON, ORLANDO, FL, US, vol. 65, 29 June 2021 (2021-06-29), US , pages 200 - 204, XP086806879, ISSN: 0883-9441, DOI: 10.1016/j.jcrc.2021.06.014
YAKAME KEN, SHOJI TAKAYO, KANAZAWA TAKAMORI, SATO MITSUNORI, KAWASAKI TATSUYA: "Severe neonatal COVID‐19 pneumonia requiring mechanical ventilation", PEDIATRICS INTERNATIONAL, JAPAN PEDIATRIC SOCIETY, HOBOKEN, USA, vol. 64, no. 1, 1 January 2022 (2022-01-01), Hoboken, USA, XP093036612, ISSN: 1328-8067, DOI: 10.1111/ped.14677
BAVARO DAVIDE FIORE, BELATI ALESSANDRA, DIELLA LUCIA, STUFANO MONICA, ROMANELLI FEDERICA, SCALONE LUCA, STOLFA STEFANIA, RONGA LUI: "Cefiderocol-Based Combination Therapy for “Difficult-to-Treat” Gram-Negative Severe Infections: Real-Life Case Series and Future Perspectives", ANTIBIOTICS, vol. 10, no. 6, pages 652, XP093036614, DOI: 10.3390/antibiotics10060652
KHAN ANIS A., SLIFER TERI R., REMINGTON JACK S.: "Effect of Trovafloxacin on Production of Cytokines by Human Monocytes", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 42, no. 7, 1 July 1998 (1998-07-01), US , pages 1713 - 1717, XP093036616, ISSN: 0066-4804, DOI: 10.1128/AAC.42.7.1713
ALIREZA PANIRI, AKHAVAN-NIAKI HALEH: "Emerging role of IL-6 and NLRP3 inflammasome as potential therapeutic targets to combat COVID-19: Role of lncRNAs in cytokine storm modulation", LIFE SCIENCE, PERGAMON PRESS, OXFORD, GB, vol. 257, 18 July 2020 (2020-07-18), GB , pages 118114, XP055724892, ISSN: 0024-3205, DOI: 10.1016/j.lfs.2020.118114
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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