Title:
NOVEL PROTEIN AND DNA THEREOF
Document Type and Number:
WIPO Patent Application WO/2004/055185
Kind Code:
A1
Abstract:
A novel protein or a polynucleotide useful as, for example, a diagnostic marker for cancer, neurodegenerative diseases, autoimmune diseases and so on. A compound inhibiting the activity of the protein or the expression of the protein gene, which is obtained by a screening method with the use of the above protein or polynucleotide, is usable as, for example, a preventive or a remedy for cancer and an apoptosis promoter.
Inventors:
TANAKA HIROSHI (JP)
KAIEDA ISAO (JP)
HONDA KOHEI (JP)
KAIEDA ISAO (JP)
HONDA KOHEI (JP)
Application Number:
PCT/JP2003/016158
Publication Date:
July 01, 2004
Filing Date:
December 17, 2003
Export Citation:
Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD (JP)
TANAKA HIROSHI (JP)
KAIEDA ISAO (JP)
HONDA KOHEI (JP)
TANAKA HIROSHI (JP)
KAIEDA ISAO (JP)
HONDA KOHEI (JP)
International Classes:
A61K31/7088; A61P3/10; A61P13/12; A61P21/04; A61P25/00; A61P25/16; A61P25/28; A61P29/00; A61P35/00; A61P37/02; A61P43/00; C07K14/47; C12N1/15; C12N1/19; C12N1/21; C12N15/12; C12Q1/68; (IPC1-7): C12N15/12; A61K31/7088; A61K39/00; A61K39/395; A61K45/00; A61K48/00; A61P3/10; A61P13/12; A61P21/04; A61P25/00; A61P25/16; A61P25/28; A61P29/00; A61P35/00; A61P37/02; A61P43/00; C07K14/82; C07K16/32; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53
Domestic Patent References:
| WO1997026001A1 | 1997-07-24 |
Other References:
XUE J-C. ET AL: "Identification of a novel testis-specific leucine-rich protein in humans and mice", BIOL. REPROD., vol. 62, no. 5, 2000, pages 1278 - 1284, XP002978049
MUELLER B.F. ET AL: "Specific binding of MAR/SAR DNA-elements by mutant p53", ONCOGENE, vol. 12, no. 9, 1996, pages 1941 - 1952, XP002110937
CADWELL C. ET AL: "The effects of wild-type p53 tumor suppressor activity and mutant p53 gain-of-function on cell growth", GENE, vol. 277, no. 1-2, 2001, pages 15 - 30, XP004311079
GOH H-S ET AL: "p53 point mutation and survival in colorectal cancer patients", CANCER RES., vol. 55, no. 22, 1995, pages 5217 - 5221, XP002978050
MUELLER B.F. ET AL: "Specific binding of MAR/SAR DNA-elements by mutant p53", ONCOGENE, vol. 12, no. 9, 1996, pages 1941 - 1952, XP002110937
CADWELL C. ET AL: "The effects of wild-type p53 tumor suppressor activity and mutant p53 gain-of-function on cell growth", GENE, vol. 277, no. 1-2, 2001, pages 15 - 30, XP004311079
GOH H-S ET AL: "p53 point mutation and survival in colorectal cancer patients", CANCER RES., vol. 55, no. 22, 1995, pages 5217 - 5221, XP002978050
Attorney, Agent or Firm:
Takahashi, Shuichi c/o Osaka Plant of Takeda Pharmaceutical Company Limited (17-85 Jusohonmachi 2-chome, Yodogawa-k, Osaka-shi Osaka, JP)
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