Title:
NOVEL PYRAZOLE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2023/191201
Kind Code:
A1
Abstract:
The present invention provides a novel pyrazole derivative compound represented by chemical formula I, a stereoisomer thereof, a solvate thereof, an isotopic variant thereof, a tautomer thereof, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising same. [Chemical formula I] (wherein A, B, and R are the same as defined in the description).
Inventors:
LEE SOO JIN (KR)
MOON SUNG HWAN (KR)
BAN SOOHO (KR)
LEE EUNSIL (KR)
SHIN EUN JUNG (KR)
GOH YOO-KYUNG (KR)
MOON SUNG HWAN (KR)
BAN SOOHO (KR)
LEE EUNSIL (KR)
SHIN EUN JUNG (KR)
GOH YOO-KYUNG (KR)
Application Number:
PCT/KR2022/012686
Publication Date:
October 05, 2023
Filing Date:
August 24, 2022
Export Citation:
Assignee:
APTABIO THERAPEUTICS INC (KR)
International Classes:
C07D401/04; A61K31/4439; A61K31/496; A61K31/5377; A61P35/00; C07D231/56; C07D401/12; C07D401/14; C07D471/04; C07D495/04
Domestic Patent References:
| WO2013127345A1 | 2013-09-06 |
Foreign References:
| KR20210091063A | 2021-07-21 | |||
| CN104177352A | 2014-12-03 | |||
| KR20220122931A | 2022-09-05 |
Other References:
LI MIN-HUI, YANG PING, YANG TAI, ZHANG KUN, LIU YANG, LIU JIN, LI LI-MEI, LUO XING-YAN, YANG SHU-XIA, ZOU QIANG, ZHANG CHONG-JIE: "A novel water-soluble benzothiazole derivative BD926 triggers ROS-mediated B lymphoma cell apoptosis via mitochondrial and endoplasmic reticulum signaling pathways", INTERNATIONAL JOURNAL OF ONCOLOGY, DEMETRIOS A. SPANDIDOS ED. & PUB, GR, vol. 49, no. 5, 1 November 2016 (2016-11-01), GR , pages 2127 - 2134, XP093096556, ISSN: 1019-6439, DOI: 10.3892/ijo.2016.3684
DATABASE Registry CAS; 7 August 2017 (2017-08-07), ANONYMOUS : "2H-Indazol-3-ol, 5-amino -4,5,6,7-tetrahydro-2 -phenyl-", XP093096568, retrieved from STN Database accession no. 2109695-62-5
DATABASE Registry CAS; 7 August 2017 (2017-08-07), ANONYMOUS : "2H-Indazol-3-ol, 5-amino -4,5,6,7-tetrahydro-2 -phenyl-", XP093096568, retrieved from STN Database accession no. 2109695-62-5
Attorney, Agent or Firm:
YOU ME PATENT AND LAW FIRM (KR)
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