Title:
NOVEL PYRIMIDINE DERIVATIVE AS BRUTON'S TYROSINE KINASE INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2024/080844
Kind Code:
A1
Abstract:
The present disclosure relates to a novel pyrimidine derivative, a solvate or stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition including any of the foregoing as an active ingredient, the pyrimidine derivative being represented by Formula I and having inhibitory activity against Bruton's tyrosine kinase. The novel pyrimidine derivative of the present disclosure effectively inhibits the enzymatic activity of Bruton's tyrosine kinase (BTK), and thus may be useful as an active ingredient in a pharmaceutical composition for preventing or treating BTK-mediated disease such as autoimmune disease or cancer: [Formula I]
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Inventors:
JANG SUN YOUNG (KR)
KANG SEOK JONG (KR)
LEE YONG TAEK (KR)
LEE GUN WOO (KR)
SUH KWEE HYUN (KR)
KANG SEOK JONG (KR)
LEE YONG TAEK (KR)
LEE GUN WOO (KR)
SUH KWEE HYUN (KR)
Application Number:
PCT/KR2023/015876
Publication Date:
April 18, 2024
Filing Date:
October 13, 2023
Export Citation:
Assignee:
HANMI PHARM CO LTD (KR)
International Classes:
C07D239/42; A61K31/505; A61K31/506; A61P35/00; A61P37/00; C07D401/10; C07D401/14; C07D403/10
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
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