Title:
NOVEL SALT OF DIMETHYL-2,3-DIHYDRO-1H-INDENE DERIVATIVE AND PROCESSES FOR PREPARING THE SAME
Document Type and Number:
WIPO Patent Application WO/2024/090917
Kind Code:
A1
Abstract:
The present invention provides a novel salt of (S)-quinuclidin-3-yl ((R)-5-(3-chloro-4-isopropoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate, i.e., (1S)-(+)-10-camphorsulfonic acid salt thereof and a process for preparing the same. The (1S)-(+)-10-camphorsulfonic acid salt of (S)-quinuclidin-3-yl ((R)-5-(3-chloro-4-isopropoxyphenyl)-2,2-dimethyl-2,3-dihydro-1H-inden-1-yl)carbamate is obtained in a crystalline form and has high purity, high stability, high water-solubility, and low hygroscopicity.
Inventors:
KANG JEONG-KI (KR)
JU HYUN (KR)
KO KYUNG-MIN (KR)
LEE JUNG-AE (KR)
HWANG YOON-AH (KR)
KIM SE-YONG (KR)
LEE JUN-SUP (KR)
SHIN SEUNG-YUB (KR)
JU HYUN (KR)
KO KYUNG-MIN (KR)
LEE JUNG-AE (KR)
HWANG YOON-AH (KR)
KIM SE-YONG (KR)
LEE JUN-SUP (KR)
SHIN SEUNG-YUB (KR)
Application Number:
PCT/KR2023/016439
Publication Date:
May 02, 2024
Filing Date:
October 23, 2023
Export Citation:
Assignee:
YUHAN CORP (KR)
GREEN CROSS CORP (KR)
GREEN CROSS CORP (KR)
International Classes:
C07D471/08
Domestic Patent References:
| WO2021096238A1 | 2021-05-20 | |||
| WO2012129084A2 | 2012-09-27 | |||
| WO1997030998A1 | 1997-08-28 | |||
| WO2019079626A1 | 2019-04-25 |
Foreign References:
| US20040002513A1 | 2004-01-01 |
Attorney, Agent or Firm:
OH, Kook-Jin (KR)
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