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Title:
NOVEL SEMI-SYNTHETIC MENINGOCOCCAL CONJUGATE VACCINE
Document Type and Number:
WIPO Patent Application WO/2015/181834
Kind Code:
A3
Abstract:
The present invention relates to novel semi-synthetic meningococcal conjugate vaccine comprising novel synthetic oligosaccharide conjugated to a carrier protein. The present invention also relates to novel synthetic meningococcal oligosaccharide and a process for its preparation.

Inventors:
GOEL, AKSHAY (Biological E. Ltd, 18/1 & 3 Azamabad,,Hyderabad - 0, Telangana, 500 02, IN)
RENUKUNTLA SANTOSH (Biological E. Ltd, 18/1 & 3 Azamabad,,Hyderabad - 0, Telangana, 500 02, IN)
KOWLAKUNTLA ESWARA (Biological E. Ltd, 18/1 & 3 Azamabad,,Hyderabad - 0, Telangana, 500 02, IN)
DETLA, MAHIMA (Biological E. Ltd, 18/1 & 3 Azamabad,,Hyderabad - 0, Telangana, 500 02, IN)
MANTENA, NARENDRA DEV (Biological E. Ltd, 18/1 & 3 Azamabad,,Hyderabad - 0, Telangana, 500 02, IN)
Application Number:
IN2015/000218
Publication Date:
January 21, 2016
Filing Date:
May 22, 2015
Export Citation:
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Assignee:
BIOLOGICAL E LIMITED (18/1 & 3, Azamabad,Hyderabad - 0, Telangana, 500 02, IN)
International Classes:
A61K39/095; A61P31/04; C07H1/00; C07H15/04; C07K1/107; C08B37/00
Domestic Patent References:
WO2010111703A12010-09-30
Other References:
KUO-CHING CHU ET AL: "Efficient and Stereoselective Synthesis of [alpha](2->9) Oligosialic Acids: From Monomers to Dodecamers", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 50, no. 40, 26 September 2011 (2011-09-26), pages 9391 - 9395, XP055209660, ISSN: 1433-7851, DOI: 10.1002/anie.201101794
GUOCHAO LIAO ET AL: "Synthesis and immunological study of [alpha]-2,9-oligosialic acid conjugates as anti-group C meningitis vaccines", CHEMICAL COMMUNICATIONS, vol. 51, no. 47, 1 January 2015 (2015-01-01), pages 9647 - 9650, XP055209892, ISSN: 1359-7345, DOI: 10.1039/C5CC01794G
Attorney, Agent or Firm:
KAYSER, AVESH (KAYSER & COMPANY, 2nd floor 20, Raja Bahadur Mansion,,Ambalal Doshi Marg, Fort,,Mumbai - 1, Maharashtra, 400 00, IN)
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