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Patent Searching and Data


Title:
NOVEL SYMBIOTIC STRAIN HAVING RESISTANCE UNDER REACTIVE OXYGEN CONDITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/040335
Kind Code:
A1
Abstract:
A novel strain of the present invention has resistance under anaerobic conditions and culture conditions containing an excessive amount of hydrogen peroxide, and therefore has resistance under reactive oxygen conditions, that is, a defense mechanism against oxidative stress. In addition, since the novel strain of the present invention has resistance under reactive oxygen conditions, it is possible to maintain the normal microbial flora present in a target organ. Therefore, the novel strain of the present invention can be extremely usefully utilized for maintaining a normal microbial flora or enhancing immune activity in an environment in which active oxygen is present.

Inventors:
YONG DONG EUN (KR)
YOON SANG SUN (KR)
Application Number:
PCT/KR2020/011192
Publication Date:
March 04, 2021
Filing Date:
August 21, 2020
Export Citation:
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Assignee:
UNIV YONSEI IACF (KR)
International Classes:
C12N1/20; A23L33/135; A61K35/745; A61P3/10; A61P29/00; A61P35/00; C12R1/01
Foreign References:
KR20180089324A2018-08-08
KR101768678B12017-08-18
US20180280453A12018-10-04
Other References:
LORENA RUIZ; PATRICIA RUAS-MADIEDO; MIGUEL GUEIMONDE; CLARA G. DE LOS REYES-GAVILÁN; ABELARDO MARGOLLES; BORJA SÁNCHEZ: "How do bifidobacteria counteract environmental challenges? Mechanisms involved and physiological consequences", GENES & NUTRITION ; STUDYING THE RELATIONSHIP BETWEEN GENETICS AND NUTRITION IN THE IMPROVEMENT OF HUMAN HEALTH, SPRINGER-VERLAG, BERLIN/HEIDELBERG, vol. 6, no. 3, 13 January 2011 (2011-01-13), Berlin/Heidelberg, pages 307 - 318, XP019931656, ISSN: 1865-3499, DOI: 10.1007/s12263-010-0207-5
PARK HO-EUN, UM HYUN-BUM, LEE WAN-KYU: "The immune enhancing effects and characteristics of Bifidobacterium longum and Bifidobacterium breve for the probiotic use in humans and animals", JOURNAL OF BIOMEDICAL TRANSLATIONAL RESEARCH, vol. 19, no. 4, 1 December 2018 (2018-12-01), pages 65 - 72, XP055786822, ISSN: 2508-1357, DOI: 10.12729/jbtr.2018.19.4.065
Attorney, Agent or Firm:
LEE, Jae Young (KR)
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