NOVEL TETRAHYDROQUINOLINE DERIVATIVES

Title:

NOVEL TETRAHYDROQUINOLINE DERIVATIVES

Document Type and Number:

WIPO Patent Application WO/2004/013104

Kind Code:

A1

Abstract:

It is intended to provide a nonsteroidal tetrahydroquinoline derivative represented by the following general formula (I), which shows a potent androgen receptor agonism particularly on skeletal muscle tissues and bone tissues without showing any excessive effect on the prostatic gland, or its salt and drugs containing the same as the active ingredient: (I) wherein R¹, R², X, Y and i are each as defined in claim 1.

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Inventors:

MIYAKAWA MOTONORI (JP)
OGURO NAO (JP)
HANADA KEIGO (JP)
FURUYA KAZUYUKI (JP)
YAMAMOTO NORIKO (JP)

Application Number:

PCT/JP2003/009815

Publication Date:

February 12, 2004

Filing Date:

August 01, 2003

Export Citation:

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Assignee:

KAKEN PHARMA CO LTD (JP)
MIYAKAWA MOTONORI (JP)
OGURO NAO (JP)
HANADA KEIGO (JP)
FURUYA KAZUYUKI (JP)
YAMAMOTO NORIKO (JP)

International Classes:

A61P5/24; A61P7/00; A61P7/06; A61P15/00; A61P15/10; A61P19/10; A61P35/00; A61P43/00; C07D221/16; C07D401/12; C07D405/12; (IPC1-7): C07D221/16; A61K31/473; A61P5/24; A61P7/00; A61P7/06; A61P15/00; A61P15/10; A61P19/10; A61P35/00; A61P43/00; C07D401/12; C07D405/12

Domestic Patent References:

WO2001058875A2

2001-08-16

Foreign References:

EP1221439A1

2002-07-10

Other References: