Title:
NOVEL THERAPEUTIC AGENT FOR PRIONOID DISEASES
Document Type and Number:
WIPO Patent Application WO/2018/105630
Kind Code:
A1
Abstract:
The present invention pertains to: a drug for preventing and/or treating cognitive dysfunction and/or a neurodegenerative disease accompanied by accumulation of prionoids, said drug comprising hemagglutinating virus of Japan envelope as an active ingredient; and a combined use of the aforesaid drug with an immune checkpoint inhibitor.
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Inventors:
KANEDA YASUFUMI (JP)
FUKUSHIMA MASANORI (JP)
NAKAJIMA TOSHIHIRO (JP)
FUKUSHIMA MASANORI (JP)
NAKAJIMA TOSHIHIRO (JP)
Application Number:
PCT/JP2017/043725
Publication Date:
June 14, 2018
Filing Date:
December 06, 2017
Export Citation:
Assignee:
UNIV OSAKA (JP)
FOUNDATION FOR BIOMEDICAL RES AND INNOVATION (JP)
GENOMIDEA INC (JP)
FOUNDATION FOR BIOMEDICAL RES AND INNOVATION (JP)
GENOMIDEA INC (JP)
International Classes:
A61K35/76; A61K39/395; A61K45/00; A61P3/10; A61P9/00; A61P21/00; A61P25/00; A61P25/16; A61P25/28; A61P27/02; A61P43/00
Domestic Patent References:
| WO2006011600A1 | 2006-02-02 | |||
| WO2015136541A2 | 2015-09-17 | |||
| WO2001057204A1 | 2001-08-09 | |||
| WO2004035779A1 | 2004-04-29 | |||
| WO2006011600A1 | 2006-02-02 | |||
| WO2005095613A1 | 2005-10-13 | |||
| WO2004039406A1 | 2004-05-13 | |||
| WO2005094878A1 | 2005-10-13 | |||
| WO2010032764A1 | 2010-03-25 | |||
| WO2001057204A1 | 2001-08-09 | |||
| WO2003014338A1 | 2003-02-20 |
Foreign References:
| JP2016236536A | 2016-12-06 | |||
| US5631237A | 1997-05-20 | |||
| JP2002065278A | 2002-03-05 | |||
| JP2011050292A | 2011-03-17 | |||
| JP2008308440A | 2008-12-25 |
Other References:
SCHENK ET AL., NATURE, vol. 400, no. 6740, 8 July 1999 (1999-07-08), pages 173 - 177
BARUCH ET AL., NATURE MEDICINE, vol. 22, no. 2, February 2016 (2016-02-01), pages 135 - 137
DZAU ET AL., PNAS, vol. 93, no. 21, 1996, pages 11421 - 11425
KANEDA ET AL., MOL. MED. TODAY, vol. 5, no. 7, 1999, pages 298 - 303
KANEDA ET AL.: "Hemagglutinating Virus of Japan (HVJ) Envelope Vector as a Versatile Gene Delivery System", MOL. THER., vol. 6, 2002, pages 219 - 226, XP002957356, DOI: doi:10.1006/mthe.2002.0647
NATURE, vol. 400, 1999, pages 173
NATURE, vol. 408, 2000, pages 979 - 982
NATURE MED, vol. 6, 2000, pages 916
NATURE MED, vol. 22, 2016, pages 135
CANCER RES., 2007
CHANG CY ET AL., ONCOTARGET, vol. 7, no. 27, 5 July 2016 (2016-07-05), pages 42195 - 42207
YUAN B ET AL., IMMUNOL LETT, vol. 179, November 2016 (2016-11-01), pages 114 - 121
YASUOKA E ET AL., J MOL MED (BERL, vol. 85, no. 3, March 2007 (2007-03-01), pages 283 - 92
SAKAUE G ET AL., J IMMUNOL., vol. 170, no. 1, 1 January 2003 (2003-01-01), pages 495 - 502
See also references of EP 3560505A4
BARUCH ET AL., NATURE MEDICINE, vol. 22, no. 2, February 2016 (2016-02-01), pages 135 - 137
DZAU ET AL., PNAS, vol. 93, no. 21, 1996, pages 11421 - 11425
KANEDA ET AL., MOL. MED. TODAY, vol. 5, no. 7, 1999, pages 298 - 303
KANEDA ET AL.: "Hemagglutinating Virus of Japan (HVJ) Envelope Vector as a Versatile Gene Delivery System", MOL. THER., vol. 6, 2002, pages 219 - 226, XP002957356, DOI: doi:10.1006/mthe.2002.0647
NATURE, vol. 400, 1999, pages 173
NATURE, vol. 408, 2000, pages 979 - 982
NATURE MED, vol. 6, 2000, pages 916
NATURE MED, vol. 22, 2016, pages 135
CANCER RES., 2007
CHANG CY ET AL., ONCOTARGET, vol. 7, no. 27, 5 July 2016 (2016-07-05), pages 42195 - 42207
YUAN B ET AL., IMMUNOL LETT, vol. 179, November 2016 (2016-11-01), pages 114 - 121
YASUOKA E ET AL., J MOL MED (BERL, vol. 85, no. 3, March 2007 (2007-03-01), pages 283 - 92
SAKAUE G ET AL., J IMMUNOL., vol. 170, no. 1, 1 January 2003 (2003-01-01), pages 495 - 502
See also references of EP 3560505A4
Attorney, Agent or Firm:
OHNO Seiji et al. (JP)
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