Title:
NOVEL THERAPEUTIC AGENTS FOR MEMBRANE TRANSPORTERS
Document Type and Number:
WIPO Patent Application WO1999064045
Kind Code:
A9
Abstract:
Disclosed are multibinding compounds that bind cell membrane transporters and modulate their activity. The multibinding compounds contain from 2 to 10 ligands covalently attached to one or more linkers.
Inventors:
JENKINS THOMAS E (US)
CHRISTENSEN BURTON G (US)
GRIFFIN JOHN H (US)
CHRISTENSEN BURTON G (US)
GRIFFIN JOHN H (US)
Application Number:
PCT/US1999/012754
Publication Date:
July 05, 2001
Filing Date:
June 07, 1999
Export Citation:
Assignee:
ADVANCED MEDICINE INC (US)
JENKINS THOMAS E (US)
CHRISTENSEN BURTON G (US)
GRIFFIN JOHN H (US)
JENKINS THOMAS E (US)
CHRISTENSEN BURTON G (US)
GRIFFIN JOHN H (US)
International Classes:
A61K45/00; A61K47/48; A61P43/00; C07B61/00; C07C217/16; C07K2/00; C40B20/00; C40B40/02; C40B50/06; G01N33/15; G01N33/50; G01N33/566; G01N33/68; (IPC1-7): A61K38/00; A61K39/00; A61K39/44; A61K39/395; A61K51/00; C07K2/00; C07K4/00; G01N33/53; G01N33/543; G01N33/566
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