Title:
NOVEL TOPICAL OESTROPROGESTATIONAL COMPOSITIONS WITH SYSTEMIC EFFECT
Document Type and Number:
WIPO Patent Application WO2002022132
Kind Code:
A8
Abstract:
The invention concerns the field of therapeutic chemistry and more particularly the production of novel galenic forms to be applied on the skin. More particularly, it concerns a topical hormonal composition with systemic effect for hormonal treatment of perimenopause and menopause as well as for treating ovarian hormonal deficiency in a woman suffering from amenorrhea. The invention is characterised in that it comprises, as active principles, a progestational derivative of the 19-norprogesterone and estradiol or one of its derivatives, a carrier for systemic delivery of said active principles, selected among the group consisting of a film-forming agent, a gelling agent and mixtures thereof, combined with a mixture of excipients suited for producing a gelled and/or film-forming pharmaceutical form.
Inventors:
GRAY GEORGES (MC)
VILLET BERTRAND (FR)
PARIS JACQUES (FR)
THOMAS JEAN-LOUIS (FR)
VILLET BERTRAND (FR)
PARIS JACQUES (FR)
THOMAS JEAN-LOUIS (FR)
Application Number:
PCT/FR2001/002865
Publication Date:
March 06, 2003
Filing Date:
September 14, 2001
Export Citation:
Assignee:
THERAMEX (MC)
GRAY GEORGES (MC)
VILLET BERTRAND (FR)
PARIS JACQUES (FR)
THOMAS JEAN-LOUIS (FR)
GRAY GEORGES (MC)
VILLET BERTRAND (FR)
PARIS JACQUES (FR)
THOMAS JEAN-LOUIS (FR)
International Classes:
A61K9/00; A61K9/06; A61K9/70; A61K31/565; A61K31/57; A61K47/00; A61K47/10; A61K47/12; A61K47/22; A61K47/34; A61K47/38; A61P5/30; A61P15/08; A61P15/12; (IPC1-7): A61K31/57; A61K9/06; A61K9/70; A61K47/00; A61P15/12
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