Title:
NOVEL TRICYCLIC AROMATIC HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/233454
Kind Code:
A1
Abstract:
Provided in the present invention are a novel tricyclic aromatic heterocyclic compound and a preparation method therefor, a pharmaceutical composition and a use thereof. Specifically, provided in the present invention is a compound as shown in formula I below, or an optical isomer, a hydrate, a solvate thereof, or a pharmaceutically acceptable salt thereof. The definitions of each group are as specified in the description. The compound of formula I can be used for treating diseases related to a PD-1/PD-L1 signaling pathway.
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Inventors:
WANG ZHE (CN)
BAI HAIYUN (CN)
QIAN ANRAN (CN)
LI DELIANG (CN)
BAI HAIYUN (CN)
QIAN ANRAN (CN)
LI DELIANG (CN)
Application Number:
PCT/CN2021/095604
Publication Date:
November 25, 2021
Filing Date:
May 24, 2021
Export Citation:
Assignee:
SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO LTD (CN)
International Classes:
C07D487/10; A61K31/4439; A61P35/00
Domestic Patent References:
| WO2018195321A1 | 2018-10-25 |
Foreign References:
| CN112457308A | 2021-03-09 | |||
| CN112457305A | 2021-03-09 | |||
| US3859350A | 1975-01-07 | |||
| US3429877A | 1969-02-25 |
Attorney, Agent or Firm:
XU&PARTNERS, LLC. (CN)
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