Title:
NOVEL TRICYCLIC, BICYCLIC, MONOCYCLIC, AND ACYCLIC AMINES AS POTENT SODIUM CHANNEL BLOCKING AGENTS
Document Type and Number:
WIPO Patent Application WO2006023757
Kind Code:
A3
Abstract:
The present invention provides acyclic, bicyclic, monocyclic, and tricyclic analogs and derivatives of tricyclic antidepressants which have sodium channel inhibiting activity. The compounds of the invention are useful as analgesics and anesthetics for diseases, conditions, and disorders where regulation of sodium channel activity can alleviate pain.
Inventors:
BROWN MILTON L (US)
Application Number:
PCT/US2005/029605
Publication Date:
August 03, 2006
Filing Date:
August 19, 2005
Export Citation:
Assignee:
UNIV VIRGINIA (US)
BROWN MILTON L (US)
BROWN MILTON L (US)
International Classes:
C07C211/03; A61K31/13; A61K31/135; A61K31/165; C07C211/17; C07C211/19; C07C211/21; C07C215/20; C07C251/12; C07C251/16
Foreign References:
| US6022895A | 2000-02-08 | |||
| US6262104B1 | 2001-07-17 | |||
| US6545057B2 | 2003-04-08 | |||
| US20030096805A1 | 2003-05-22 |
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