Title:
NOVEL TYPE II CITRATE SYNTHASE VARIANT, AND METHOD FOR PRODUCING L-LYSINE USING SAME
Document Type and Number:
WIPO Patent Application WO/2022/163912
Kind Code:
A1
Abstract:
The present application relates to a type II citrate synthase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
Inventors:
PARK GOUN (KR)
KIM BYEONG SOO (KR)
LEE HAN HYOUNG (KR)
BAE HYUN WON (KR)
BYUN HYO JEONG (KR)
HUH LAN (KR)
YOO HYERYUN (KR)
KIM BINA (KR)
SON SUNG KWANG (KR)
KIM BYEONG SOO (KR)
LEE HAN HYOUNG (KR)
BAE HYUN WON (KR)
BYUN HYO JEONG (KR)
HUH LAN (KR)
YOO HYERYUN (KR)
KIM BINA (KR)
SON SUNG KWANG (KR)
Application Number:
PCT/KR2021/004158
Publication Date:
August 04, 2022
Filing Date:
April 02, 2021
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
International Classes:
C12N9/10; C07K14/34; C12N9/02; C12N9/04; C12N9/12; C12N15/77; C12P13/08
Domestic Patent References:
| WO2008006680A2 | 2008-01-17 | |||
| WO2008082181A1 | 2008-07-10 |
Foreign References:
| KR101582008B1 | 2015-12-31 | |||
| KR100838035B1 | 2008-06-12 | |||
| JPH07121228B2 | 1995-12-25 | |||
| US9556463B2 | 2017-01-31 | |||
| US7662943B2 | 2010-02-16 | |||
| US10584338B2 | 2020-03-10 | |||
| US10273491B2 | 2019-04-30 | |||
| KR20200136813A | 2020-12-08 |
Other References:
DATABASE Protein 28 November 2019 (2019-11-28), "citrate synthase [Corynebacterium glutamicum] ", XP055945528, retrieved from NCBI Database accession no. WP_011013914.1
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL.: "EMBOSS: The European Molecular Biology Open Software Suite", TRENDS GENET, vol. 16, 2000, pages 276 - 277, XP004200114, DOI: 10.1016/S0168-9525(00)02024-2
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
"Guide to Huge Computers", 1994, ACADEMIC PRESS
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas Of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, pages 443 - 453
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
NAKASHIMA N. ET AL.: "Bacterial cellular engineering by genome editing and gene silencing", INT J MOL SCI., vol. 15, no. 2, 2014, pages 2773 - 2793, XP055376889, DOI: 10.3390/ijms15022773
WEINTRAUB, H. ET AL.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS-TRENDS IN GENETICS, vol. 1, 1986, pages 1
SITNICKA ET AL.: "Functional Analysis of Genes", ADVANCES IN CELL BIOLOGY, vol. 2, 2010, pages 1 - 16
SAMBROOK ET AL., MOLECULAR CLONING, 2012
See also references of EP 4056694A4
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL.: "EMBOSS: The European Molecular Biology Open Software Suite", TRENDS GENET, vol. 16, 2000, pages 276 - 277, XP004200114, DOI: 10.1016/S0168-9525(00)02024-2
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
"Guide to Huge Computers", 1994, ACADEMIC PRESS
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas Of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, pages 443 - 453
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
NAKASHIMA N. ET AL.: "Bacterial cellular engineering by genome editing and gene silencing", INT J MOL SCI., vol. 15, no. 2, 2014, pages 2773 - 2793, XP055376889, DOI: 10.3390/ijms15022773
WEINTRAUB, H. ET AL.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS-TRENDS IN GENETICS, vol. 1, 1986, pages 1
SITNICKA ET AL.: "Functional Analysis of Genes", ADVANCES IN CELL BIOLOGY, vol. 2, 2010, pages 1 - 16
SAMBROOK ET AL., MOLECULAR CLONING, 2012
See also references of EP 4056694A4
Attorney, Agent or Firm:
YOU ME PATENT AND LAW FIRM (KR)
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