NOVEL UREA DERIVATIVE COMPOUND AS RON INHIBITOR

WIPO Patent Application WO/2022/270979

A1

The present invention relates to a novel compound as a protein kinase inhibitor, especially as a RON inhibitor.

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JP2014532626	Compounds and methods that enhance the innate immune response
WO/2011/158833	AGENT FOR TREATING HCV INFECTION

HAM YOUNG JIN (KR)
CHO JOONG HEUI (KR)
YOON HONG BIN (KR)
KIM JUNG JOON (KR)
KWAK YOUNG SHIN (KR)
KIM GYEONG HWAN (KR)
LEE JU HYUN (KR)

PCT/KR2022/009042

December 29, 2022

June 24, 2022

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LG CHEMICAL LTD (KR)

C07D471/04; A61K31/437; A61K31/444; A61K31/4545; A61K31/4725; A61K31/501; A61K31/506; A61P35/00; A61P37/00

WO2006043090A1	2006-04-27
WO2007125330A1	2007-11-08
WO2009130487A1	2009-10-29

NOURRY ARNAUD, ZAMBON ALFONSO, DAVIES LAWRENCE, NICULESCU-DUVAZ ION, DIJKSTRA HARMEN P., MÉNARD DELPHINE, GAULON CATHERINE, NICULE: "BRAF Inhibitors Based on an Imidazo[4,5]pyridin-2-one Scaffold and a Meta Substituted Middle Ring", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 53, no. 5, 11 March 2010 (2010-03-11), US , pages 1964 - 1978, XP093016966, ISSN: 0022-2623, DOI: 10.1021/jm901509a
WU XIAOYUN, WAN SHANHE, ZHONGHUANG LI, YANG LIN, JIAJIE ZHANG, WU SHUGUANG: "3D-QSAR study on 2,3-dihydroimidazo[4,5]-pyridin-2-one derivatives with a meta substitution pattern as V600E BRAF inhibitors", MEDICINAL CHEMISTRY RESEARCH, vol. 23, no. 2, 12 June 2013 (2013-06-12), pages 587 - 602, XP093016964, DOI: 10.1007/s00044-013-0633-1

BAE, KIM & LEE IP (KR)

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