Title:
NOVEL USE OF LIPOCALIN 2 FOR TREATING BRAIN DAMAGE
Document Type and Number:
WIPO Patent Application WO/2010/021516
Kind Code:
A2
Abstract:
The present invention relates to a composition containing a lipocalin 2 (LCN2) inhibitor for treating brain damage and a method for treating brain damage by administering the composition. When the central nervous system (CNS) is injured, astrocytes are activated and astrocytosis is induced. Astrocytosis is a main factor causing nerve cell damage and suppressing regeneration of damaged nerve cells. Since the LCN2 mainly induces astrocytosis, additional damage of nerve cells after brain damage is prevented using the LCN2 inhibitor. Also, the regeneration of damaged nerve cells can be promoted.
Inventors:
SUK, Kyoung Ho (2 Metro Palace Apt, Manchon-dong Suseong-gu, Daegu 706-020, 706-020, KR)
석경호 (대구 수성구 만촌동 메트로팔레스, 706-020 Daegu, 706-020, KR)
석경호 (대구 수성구 만촌동 메트로팔레스, 706-020 Daegu, 706-020, KR)
Application Number:
KR2009/004676
Publication Date:
February 25, 2010
Filing Date:
August 21, 2009
Export Citation:
Assignee:
KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION (1370, Sangyeok-dong Buk-gu, Daegu 702-010, 702-010, KR)
경북대학교 산학협력단 (대구 북구 산격동 1370번지, 702-010 Daegu, 702-010, KR)
SUK, Kyoung Ho (2 Metro Palace Apt, Manchon-dong Suseong-gu, Daegu 706-020, 706-020, KR)
경북대학교 산학협력단 (대구 북구 산격동 1370번지, 702-010 Daegu, 702-010, KR)
SUK, Kyoung Ho (2 Metro Palace Apt, Manchon-dong Suseong-gu, Daegu 706-020, 706-020, KR)
International Classes:
A61K39/395; A61K39/395
Attorney, Agent or Firm:
KIM, Soon Woong (209 KICOX Venture Center, 188-5 Guro-dong, Guro-gu, Seoul 152-050, 152-050, KR)
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