Title:
NOVEL VACCINE COMPOSITIONS FOR PORCINE EPIDEMIC DIARRHEA VIRUS AND PORCINE DELTACORONAVIRUS
Document Type and Number:
WIPO Patent Application WO/2016/007576
Kind Code:
A8
Abstract:
The present invention is directed to novel immunogenic compositions that protect swine from disease caused by porcine epidemic diarrhea virus (PEDV). The present invention is also directed to novel immunogenic compositions that protect swine from disease caused by porcine deltacoronavirus (PDCoV), alone or as combination vaccine to protect against PEDV. The compositions of the invention provide killed viruses whose effectiveness is enhanced by the selection of preferred adjuvants. Novel culture methods are also employed to increase reproducible yield of cultured viruses. Live vaccines are also provided from the Calaf14 PEDV isolate.
Inventors:
MARX JACQUELINE GAYLE (US)
HARDHAM JOHN MORGAN (US)
DOMINOWSKI PAUL J (US)
RAPP GABRIELSON VICKI JON (US)
BALASCH SANUY MONICA (US)
CABANA SUMSI MARTA (US)
PLAJA DILME LAIA (US)
URNIZA HOSTENCH ALICIA (US)
ROMERO GALINDO OSCAR (US)
HARDHAM JOHN MORGAN (US)
DOMINOWSKI PAUL J (US)
RAPP GABRIELSON VICKI JON (US)
BALASCH SANUY MONICA (US)
CABANA SUMSI MARTA (US)
PLAJA DILME LAIA (US)
URNIZA HOSTENCH ALICIA (US)
ROMERO GALINDO OSCAR (US)
Application Number:
PCT/US2015/039475
Publication Date:
December 22, 2016
Filing Date:
July 08, 2015
Export Citation:
Assignee:
ZOETIS SERVICES LLC (US)
International Classes:
A61K39/215; A61K39/00; C07K14/165; C12N7/00
Attorney, Agent or Firm:
DONAHUE, E., Victor et al. (10 Sylvan WayParsippany, NJ, US)
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