Title:
NRF2 ACTIVATOR
Document Type and Number:
WIPO Patent Application WO/2018/140738
Kind Code:
A8
Abstract:
Provided are compounds of Formula I, or pharmaceutically acceptable salts thereof, which are activators of nuclear factor erythroid 2 (NF-E2) -related factor 2 (Nrf2) and are useful to treat diseases caused by oxidative stress, such as neurodegenerative diseases or inflammation. Also provided are methods for their use and production.
Inventors:
CAPACCI ANDREW (US)
LIN EDWARD (US)
LUCAS BRIAN (US)
LIN EDWARD (US)
LUCAS BRIAN (US)
Application Number:
PCT/US2018/015465
Publication Date:
August 15, 2019
Filing Date:
January 26, 2018
Export Citation:
Assignee:
BIOGEN MA INC (US)
International Classes:
C07D311/74; A61K31/352; A61K31/47; C07D319/16
Attorney, Agent or Firm:
DAVIS, Steven G. et al. (US)
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