Title:
NRF2 REGULATORS
Document Type and Number:
WIPO Patent Application WO/2016/202253
Kind Code:
A1
Abstract:
Provided are aryl analogs，pharmaceutical compositions containing them and their use as NRF2 regulators.
Inventors:
KERNS JEFFREY K (US)
CALLAHAN JAMES FRANCIS (US)
YAN HONGXING (US)
HEIGHTMAN THOMAS DANIEL (GB)
GRIFFITHS-JONES CHARLOTTE MARY (GB)
WOOLFORD ALISON JO-ANNE (GB)
LI TINDY (US)
LAKDAWALA SHAH AMI (US)
DAVIS RODERIC S (US)
NORTON DAVID (GB)
GOODWIN NICOLE CATHLEEN (US)
JIN YUN (CN)
CALLAHAN JAMES FRANCIS (US)
YAN HONGXING (US)
HEIGHTMAN THOMAS DANIEL (GB)
GRIFFITHS-JONES CHARLOTTE MARY (GB)
WOOLFORD ALISON JO-ANNE (GB)
LI TINDY (US)
LAKDAWALA SHAH AMI (US)
DAVIS RODERIC S (US)
NORTON DAVID (GB)
GOODWIN NICOLE CATHLEEN (US)
JIN YUN (CN)
Application Number:
PCT/CN2016/085806
Publication Date:
December 22, 2016
Filing Date:
June 15, 2016
Export Citation:
Assignee:
GLAXOSMITHKLINE IP DEV LTD (GB)
ASTEX THERAPEUTICS LTD (GB)
GLAXOSMITHKLINE (CHINA) R&D CO LTD (CN)
ASTEX THERAPEUTICS LTD (GB)
GLAXOSMITHKLINE (CHINA) R&D CO LTD (CN)
International Classes:
C07D417/10; C07C15/16; C07D249/04; C07D249/18; C07D403/10
Domestic Patent References:
| WO2015092713A1 | 2015-06-25 | |||
| WO2014145642A2 | 2014-09-18 | |||
| WO2013067036A1 | 2013-05-10 | |||
| WO2013122028A1 | 2013-08-22 |
Other References:
See also references of EP 3307739A4
Attorney, Agent or Firm:
KING & WOOD MALLESONS (East Tower World Financial Center,No. 1 Dongsanhuan Zhonglu, Chaoyang District, Beijing 0, CN)
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