Title:
NUCLEIC ACID DETECTION ELEMENT, AND NUCLEIC ACID DETECTION METHOD
Document Type and Number:
WIPO Patent Application WO/2018/047771
Kind Code:
A1
Abstract:
The purpose of the present invention is to solve the problem that existing DNA detection element structures merely show low detection sensitivity and poor heat resistance. A nucleic acid detection element for detecting a nucleic acid having a primer part in a solution, said element at least comprising a substrate, an intermediate layer differing from the substrate, and a layer of a compound capable of binding to the nucleic acid, in this order.
Inventors:
NAKATANI KAZUHIKO (JP)
VERMA RAJIV KUMAR (JP)
SABANI NORHAYATI BINTI (JP)
TAKEI FUMIE (JP)
SAKAI MASAHIRO (JP)
NOBUSAWA KAZUYUKI (JP)
YAMASHITA ICHIRO (JP)
VERMA RAJIV KUMAR (JP)
SABANI NORHAYATI BINTI (JP)
TAKEI FUMIE (JP)
SAKAI MASAHIRO (JP)
NOBUSAWA KAZUYUKI (JP)
YAMASHITA ICHIRO (JP)
Application Number:
PCT/JP2017/031803
Publication Date:
March 15, 2018
Filing Date:
September 04, 2017
Export Citation:
Assignee:
UNIV OSAKA (JP)
PANASONIC CORP (JP)
PANASONIC CORP (JP)
International Classes:
C12M1/00; C12M1/34; C12Q1/68; G01N27/414; G01N27/416
Domestic Patent References:
| WO2011004136A1 | 2011-01-13 | |||
| WO2001068834A1 | 2001-09-20 |
Foreign References:
| JP2016047777A | 2016-04-07 |
Other References:
OKANO, M. ET AL.: "Detection of fluorescence molecule-DNA binding based on a graphene FET", THE PREPRINTS OF THE 75TH JSAP AUTUMN MEETING, 2014, pages 17 - 151
OKANO, M. ET AL.: "Electrical detection of binding and separation between modified graphene FETs and DNA", THE PREPRINTS OF THE 62TH JSAP SPRING MEETING, 2015, pages 11 - 149
OKAMOTO, S. ET AL.: "Fragment-modified graphene FET for highly sensitive detection of antigen-antibody reaction", THE 14TH INTERNATIONAL MEETING ON CHEMICAL SENSORS, 2012, pages 519 - 522, XP055473812, ISBN: 978-1-62993-526-3
MAEHASHI, K. ET AL.: "Biological sensors based on graphene devices", BIO INDUSTRY, vol. 32, no. 1, 2015, pages 29 - 34, ISSN: 0910-6545
MATSUMOTO, KAZUHIKO: "Strategic Basic Research Programs CREST Study area ''Establishment of Foundation for Nano-interface Technology", IMPLEMENTATION OF QUANTUM NANO-DEVICES BY QUANTUM INTERFACE SUPPRESSION, October 2008 (2008-10-01), pages 1 - 10, Retrieved from the Internet
WANG, L. ET AL.: "Graphene sheets, polyaniline and AuNPs based DNA sensor for electrochemical determination of BCR/ABL fusion gene with functional hairpin probe", BIOSENSORS AND BIOELECTRONICS, vol. 51, 2014, pages 201 - 207, XP055473819, ISSN: 0956-5663
OKANO, M. ET AL.: "Electrical detection of binding and separation between modified graphene FETs and DNA", THE PREPRINTS OF THE 62TH JSAP SPRING MEETING, 2015, pages 11 - 149
OKAMOTO, S. ET AL.: "Fragment-modified graphene FET for highly sensitive detection of antigen-antibody reaction", THE 14TH INTERNATIONAL MEETING ON CHEMICAL SENSORS, 2012, pages 519 - 522, XP055473812, ISBN: 978-1-62993-526-3
MAEHASHI, K. ET AL.: "Biological sensors based on graphene devices", BIO INDUSTRY, vol. 32, no. 1, 2015, pages 29 - 34, ISSN: 0910-6545
MATSUMOTO, KAZUHIKO: "Strategic Basic Research Programs CREST Study area ''Establishment of Foundation for Nano-interface Technology", IMPLEMENTATION OF QUANTUM NANO-DEVICES BY QUANTUM INTERFACE SUPPRESSION, October 2008 (2008-10-01), pages 1 - 10, Retrieved from the Internet
WANG, L. ET AL.: "Graphene sheets, polyaniline and AuNPs based DNA sensor for electrochemical determination of BCR/ABL fusion gene with functional hairpin probe", BIOSENSORS AND BIOELECTRONICS, vol. 51, 2014, pages 201 - 207, XP055473819, ISSN: 0956-5663
Attorney, Agent or Firm:
SHOBAYASHI Masayuki et al. (JP)
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