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Title:
NUCLEIC ACID PRIMERS AND PROBES FOR DETECTING HIV-1 AND HIV-2
Document Type and Number:
WIPO Patent Application WO1998058086
Kind Code:
A3
Abstract:
Provided herein are primer/probe sets useful for detecting HIV (i.e. either or both HIV 1 or HIV 2) in a test sample. The primer/probe sets can be employed according to nucleic acid amplification procedures including PCR or RT PCR. The primer/probe sets can also be provided in the form of a kit with other reagents for performing a nucleic acid amplification reaction.

Inventors:
KROEGER PAUL E
ABRAVAYA KLARA
ESPING CLAUDIA A CYGAN
GORZOWSKI JACEK J
HOENLE ROBERT J
MOORE JENNIFER J
Application Number:
PCT/US1998/011652
Publication Date:
March 11, 1999
Filing Date:
June 04, 1998
Export Citation:
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Assignee:
ABBOTT LAB (US)
International Classes:
C12N15/09; C12Q1/68; C12Q1/70; (IPC1-7): C12Q1/70
Domestic Patent References:
WO1993013223A11993-07-08
WO1996002557A11996-02-01
WO1995014109A11995-05-26
WO1994003635A11994-02-17
WO1997007235A21997-02-27
Foreign References:
EP0727497A11996-08-21
EP0617132A21994-09-28
EP0404625A21990-12-27
US5629153A1997-05-13
FR2652091A11991-03-22
US5569582A1996-10-29
Other References:
GINGERAS T R ET AL.: "Use of self-sustained sequence replication amplification reaction to analyze and detect mutations in zidovudine-resistant human immunodeficiency virus", THE JOURNAL OF INFECTIOUS DISEASES, vol. 164, no. 6, 1991, pages 1066 - 1074, XP002086953
RESPESS R A ET AL.: "Detection of genetically diverse human immunodeficiency virus type 1 group M and O isolates by PCR", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 35, no. 5, 1997, pages 1284 - 1286, XP002086954
CARMAN W F ET AL: "DETECTION OF ENZYMATICALLY AMPLIFIED HUMAN IMMUNODEFICIENCY VIRUS DNA BY OLIGONUCLEOTIDE SOLUTION HYBRIDIZATION AND BY INCORPORATION OF RADIOLABELED DEOXYNUCLEOTIDES", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 27, no. 11, November 1989 (1989-11-01), pages 2570 - 2573, XP000619830
BROWN V ET AL.: "Detection of HIV-1 and 2 infection by the polymerase chain reaction PCR", ABSTRACT OF THE GENERAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY, vol. 91, no. 0, 1991, pages 335, XP002086955
ABRAVAYA K ET AL.: "Research investigations into the suitability of the LCx platform for detection of bloodborne viruses", INFUSION THERAPY AND TRANSFUSION MEDICINE, vol. 25, 1998, pages 170 - 177, XP002086956
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