NUCLEIC ACIDS AND CORRESPONDING PROTEINS ENTITLED 158P3D2 USEFUL IN TREATMENT AND DETECTION OF CANCER

Title:

NUCLEIC ACIDS AND CORRESPONDING PROTEINS ENTITLED 158P3D2 USEFUL IN TREATMENT AND DETECTION OF CANCER

Document Type and Number:

WIPO Patent Application WO2006055004

Kind Code:

A8

Abstract:

A novel gene 158P3D2 and its encoded protein, and variants thereof, are described wherein 158P3D2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table 1. Consequently, 158P3D2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 158P3D2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 158P3D2 can be used in active or passive immunization.

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Inventors:

RAITANO ARTHUR B (US)
JAKOBOVITS AYA (US)
CHALLITA-EID PIA M (US)
KANNER STEVEN B (US)
GE WANGMAO (US)
PEREZ-VILLAR JUAN J (US)
MORRISON ROBERT KENDALL (US)

Application Number:

PCT/US2004/039083

Publication Date:

August 24, 2006

Filing Date:

November 19, 2004

Export Citation:

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Assignee:

AGENSYS INC (US)
RAITANO ARTHUR B (US)
JAKOBOVITS AYA (US)
CHALLITA-EID PIA M (US)
KANNER STEVEN B (US)
GE WANGMAO (US)
PEREZ-VILLAR JUAN J (US)
MORRISON ROBERT KENDALL (US)

International Classes:

C07K14/47

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