Title:
NUCLEIC ACIDS, PROTEINS, AND ANTIBODIES
Document Type and Number:
WIPO Patent Application WO2001054472
Kind Code:
A3
Abstract:
The present invention relates to novel proteins. More specifically, isolated nucleic acid molecules are provided encoding novel polypeptides. Novel polypeptides and antibodies that bind to these polypeptides are provided. Also provided are vectors, host cells, and recombinant and synthetic methods for producing human polynucleotides and/or polypeptides, and antibodies. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing and/or prognosing disorders related to these novel polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further relates to methods and/or compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
Inventors:
ROSEN CRAIG A (US)
BARASH STEVEN C (US)
RUBEN STEVEN M (US)
BARASH STEVEN C (US)
RUBEN STEVEN M (US)
Application Number:
PCT/US2001/001307
Publication Date:
January 31, 2002
Filing Date:
January 17, 2001
Export Citation:
Assignee:
HUMAN GENOME SCIENCES INC (US)
ROSEN CRAIG A (US)
BARASH STEVEN C (US)
RUBEN STEVEN M (US)
ROSEN CRAIG A (US)
BARASH STEVEN C (US)
RUBEN STEVEN M (US)
International Classes:
C07K14/47; C12N15/60; A61K38/00; (IPC1-7): C12Q1/68; C07H21/02
Domestic Patent References:
| WO1992015602A1 | 1992-09-17 |
Other References:
LEE ET AL.: "Transcriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumor cell lines", JOURNAL OF CELL BIOLOGY, vol. 18, 1992, pages 1213 - 1221, XP002946828
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