NUCLEUS PULPOSUS PROGENITOR CELL CULTURE MEDIUM, PREPARATION METHOD THEREFOR AND USE THEREOF

Title:

NUCLEUS PULPOSUS PROGENITOR CELL CULTURE MEDIUM, PREPARATION METHOD THEREFOR AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2021/129030

Kind Code:

A1

Abstract:

Provided are a nucleus pulposus progenitor cell culture medium, a preparation method therefor and use thereof. The culture medium consists of a DMEM medium, an F12 medium, proline, sodium pyruvate, vitamin C, an insulin growth factor, FGF2, transferrin, an ROCK inhibitor, a p38 inhibitor, and a transforming growth factor β signal pathway inhibitor.

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Inventors:

LIANG CHENGZHEN (CN)
XIA KAISHUN (CN)
ZHANG YUANG (CN)
LI FANGCAI (CN)
CHEN QIXIN (CN)

Application Number:

PCT/CN2020/119101

Publication Date:

July 01, 2021

Filing Date:

September 29, 2020

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Assignee:

UNIV ZHEJIANG (CN)

International Classes:

C12N5/0797

Foreign References:

CN111019896A	2020-04-17
CN109988744A	2019-07-09
US20190127707A1	2019-05-02

Other References:

TEKARI ADEL, CHAN SAMANTHA C. W., SAKAI DAISUKE, GRAD SIBYLLE, GANTENBEIN BENJAMIN: "Angiopoietin-1 receptor Tie2 distinguishes multipotent differentiation capability in bovine coccygeal nucleus pulposus cells", STEM CELL RESEARCH & THERAPY, vol. 7, no. 1, 1 December 2016 (2016-12-01), XP055796514, DOI: 10.1186/s13287-016-0337-9

Attorney, Agent or Firm:

HANGZHOU QIUSHI PATENT OFFICE CO., LTD. (CN)

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