Title:
OBSERVATION METHOD USING NON-HUMAN MAMMALIAN CEREBRAL INFARCTION MODEL, AND OBSERVATION DEVICE USING NON-HUMAN MAMMALIAN CEREBRAL INFARCTION MODEL
Document Type and Number:
WIPO Patent Application WO/2019/039438
Kind Code:
A1
Abstract:
[Problem] To provide a method for observation by a non-human mammalian cerebral infarction model, and a device for observation by a non-human mammalian cerebral infarction model. [Solution] The problem addressed by the present invention is solved by a method for observing a non-human mammal in a state of cerebral infarction, the method comprising performing a procedure to make the brain of an anesthetized non-human mammal observable using a remote bilateral common carotid artery occlusion model for the non-human mammal, and observing, temporally/spatially and in real time, the cerebral infarction pathology from before the onset of infarction in a cerebral blood vessel until ischemia/abnormal contraction/reperfusion through use of a two-photon laser microscope.
Inventors:
YATA KENICHIRO (JP)
TOMIMOTO HIDEKAZU (JP)
MIZOGUCHI AKIRA (JP)
INAGAKI MASAKI (JP)
TOMIMOTO HIDEKAZU (JP)
MIZOGUCHI AKIRA (JP)
INAGAKI MASAKI (JP)
Application Number:
PCT/JP2018/030683
Publication Date:
February 28, 2019
Filing Date:
August 20, 2018
Export Citation:
Assignee:
UNIV MIE (JP)
International Classes:
A61B10/00; A01K67/027; A61B5/0285; A61K31/417; A61K45/00; A61P9/10; A61P43/00; G01N33/15; G01N33/50
Domestic Patent References:
| WO2017048191A1 | 2017-03-23 | |||
| WO2004052181A2 | 2004-06-24 |
Foreign References:
| JP2012168492A | 2012-09-06 | |||
| JP2004359675A | 2004-12-24 | |||
| JP2004517874A | 2004-06-17 | |||
| JP2008262031A | 2008-10-30 | |||
| JP2008534601A | 2008-08-28 |
Attorney, Agent or Firm:
KOBAYASHI, Youhei (JP)
Download PDF:
Previous Patent: PRESS METHOD AND PRESS DEVICE
Next Patent: FUSION PROTEIN OF DCTN1 PROTEIN WITH RET PROTEIN
Next Patent: FUSION PROTEIN OF DCTN1 PROTEIN WITH RET PROTEIN