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Title:
OIL-IN-WATER TYPE EMULSION LOTION CONTAINING 22-OXA-1α,25-DIHYDROXYVITAMIN D3 AND METHOD OF TREATING SKIN DISEASE BY USING THE SAME
Document Type and Number:
WIPO Patent Application WO/2007/086582
Kind Code:
A1
Abstract:
It is intended to provide a lotion which has the high transdermal absorbability of maxacalcitol, can contain maxacalcitol in a chemically stable state and suffers from little dripping when applied to the head. A basic oil-in-water type emulsion lotion containing 22-oxa-1α,25-dihydroxyvitamin D3, a medium-chain fatty acid triglyceride, a nonionic surfactant and a water-soluble thickener; and a method of treating skin diseases by using the same.

Inventors:
HARADA SHIN-ICHI (JP)
Application Number:
PCT/JP2007/051502
Publication Date:
August 02, 2007
Filing Date:
January 30, 2007
Export Citation:
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Assignee:
MARUHO KK (JP)
HARADA SHIN-ICHI (JP)
International Classes:
A61K31/593; A61K8/06; A61K8/34; A61K8/37; A61K8/41; A61K8/67; A61K9/107; A61K47/14; A61P17/00; A61P17/06; A61Q19/00
Domestic Patent References:
WO1999029326A11999-06-17
WO1999029325A11999-06-17
WO1999044617A11999-09-10
WO2002017932A12002-03-07
WO1998056388A11998-12-17
WO1999029325A11999-06-17
WO1999044617A11999-09-10
WO2002017932A12002-03-07
Foreign References:
JPS61267550A1986-11-27
Other References:
DRAIZE, J.H.: "Association of Food and Drug Officials of the United State", 1959, article "Appraisal of the safety of chemical in foods, drugs and cosmetics", pages: 49 - 51
KAY, J.H.; VALANDRA, J.C.: "Interpretation of eye irritation tests", J SOC. COSM, CHEM., 1962, pages 281 - 289
Attorney, Agent or Firm:
SHAMOTO, Ichio et al. (Section 206 New Ohtemachi Bldg., 2-1, Ohtemachi 2-chom, Chiyoda-ku Tokyo 04, JP)
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