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Title:
OLIGONUCLEOTIDES FOR SARS-COV-2 MODULATION
Document Type and Number:
WIPO Patent Application WO/2021/243291
Kind Code:
A3
Abstract:
This disclosure relates to novel SARS-CoV-2 targeting sequences. Novel SARS-CoV-2 targeting oligonucleotides for the treatment of SARS-CoV-2 infection are also provided.

Inventors:
KHVOROVA ANASTASIA (US)
WATTS JONATHON (US)
KENNEDY ZACHARY (US)
BISCANS ANNABELLE (US)
GODINHO BRUNO (US)
FERGUSON CHANTAL (US)
ECHEVERRIA MORENO DIMAS (US)
YAMADA KEN (US)
O'REILLY DANIEL (US)
MONOPOLI KATHRYN (US)
HARIHARAN VIGNESH NARAYAN (US)
TANG QI (US)
DAVIS SARAH (US)
HILDEBRAND SAMUEL (US)
LY SOCHEATA (US)
SHIN MINWOOK (US)
KRISHNAMURTHY PRANATHI MEDA (US)
MCHUGH NICHOLAS (US)
SOUSA JACQUELYN (US)
CAIAZZIA JILLIAN (US)
THILLIER YANN (US)
DEVI GITALI (US)
Application Number:
PCT/US2021/035002
Publication Date:
February 10, 2022
Filing Date:
May 28, 2021
Export Citation:
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Assignee:
UNIV MASSACHUSETTS (US)
International Classes:
C12N15/113; A61K31/7105; A61K31/712; C12Q1/6876; C12Q1/6888
Domestic Patent References:
WO1997005256A21997-02-13
Foreign References:
US20090226921A12009-09-10
US20110287025A12011-11-24
US20070238681A12007-10-11
US20170312367A12017-11-02
US20200123543A12020-04-23
US20210277489A12021-09-09
Other References:
ANONYMOUS: "Protocol: Real-time RT-PCR assays for the detection of SARS-CoV-2 Institut Pasteur", WORLD HEALTH ORGANIZATION, 3 March 2020 (2020-03-03), pages 1 - 4, XP055888027, Retrieved from the Internet
WU ET AL.: "A new coronavirus associated with human respiratory disease in China", NATURE, vol. 579, 3 February 2020 (2020-02-03), pages 265 - 269, XP037525882, Retrieved from the Internet DOI: 10.1038/s41586-020-2008-3
JUNG YU JIN; PARK GUN-SOO; MOON JUN HYE; KU KEUNBON; BEAK SEUNG-HWA; KIM SEIL; PARK EDMOND CHANGKYUN; PARK DAEUI; LEE JONG-HWAN; B: "Comparative analysis of primer-probe sets for the laboratory confirmation of SARS-CoV-2", BIORXIV, 27 February 2020 (2020-02-27), pages 1 - 13, XP055854850, Retrieved from the Internet
Attorney, Agent or Firm:
SPELLBERG, Michael et al. (US)
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