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Title:
OLIGOSACCHARIDE COMPOSITIONS AND METHODS OF USE THEREOF FOR REDUCING AMMONIA LEVELS
Document Type and Number:
WIPO Patent Application WO/2020/041531
Kind Code:
A3
Abstract:
Aspects of the disclosure relate to oligosaccharide compositions and methods of making the same. Also provided are methods of using oligosaccharide compositions as microbiome metabolic therapies for reducing ammonia levels and for the treatment of hyperammonemia-related diseases (e.g., urea cycle disorders and hepatic encephalopathy).

Inventors:
LIU CHRISTOPHER MATTHEW (US)
GEREMIA JOHN M (US)
LIOUBOMIROV ANASTASIA (US)
HECHT MAX (US)
Application Number:
PCT/US2019/047595
Publication Date:
March 26, 2020
Filing Date:
August 21, 2019
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Assignee:
KALEIDO BIOSCIENCES INC (US)
International Classes:
C08B37/00; C08L5/02
Domestic Patent References:
WO2016007778A12016-01-14
WO1998041544A11998-09-24
Foreign References:
EP2248907A12010-11-10
US6559302B12003-05-06
Other References:
RUIQING XIAO ET AL: "Chemical synthesis of polysaccharides and polysaccharide mimetics", PROGRESS IN POLYMER SCIENCE., vol. 74, 1 November 2017 (2017-11-01), GB, pages 78 - 116, XP055554770, ISSN: 0079-6700, DOI: 10.1016/j.progpolymsci.2017.07.009
Attorney, Agent or Firm:
YOUNG, Daniel, W. et al. (US)
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