Title:
OPHTHALMIC COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2018/194119
Kind Code:
A1
Abstract:
Provided is an ophthalmic composition from which sesame oil or castor oil can be released easily by the dilution with a tear fluid and therefore the sesame oil or castor oil can be supplied to a tear oil layer. An ophthalmic composition containing (A) at least one oil selected from (A-1) sesame oil and (A-2) castor oil and (B) a nonionic surfactant selected from (B-1) polyoxyethylene castor oil, (B-2) polyoxyethylene hydrogenated castor oil and (B-3) another nonionic surfactant, wherein the blend ratios of these components by mass meet the following requirement: 0.05 ≤ [(B-1)+(B-2)+(B-3)]/(A)[(B-1)/0.5+(B-2)/0.5+(B-3)/0.05]/[(A-1)+(A-2)]×(A-1)/[(A-1)+(A-2)]+[(B-1)/0.2+(B-2)/0.25+(B-3)/0.05]/[(A-1)+(A-2)]×(A-2)/[(A-1)+(A-2)] ≤ 10.0, and the permeability of the composition is 70% or more.
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| WO/2006/116485 | TRPV1 AGONIST COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME |
| WO/1999/001044 | PALATABLE ELEMENTAL MEDICAL FOOD |
Inventors:
TANAKA MEGUMI (JP)
YOSHIDA MASATAKA (JP)
TAKAMURA YUMI (JP)
YOSHIDA MASATAKA (JP)
TAKAMURA YUMI (JP)
Application Number:
PCT/JP2018/016107
Publication Date:
October 25, 2018
Filing Date:
April 19, 2018
Export Citation:
Assignee:
LION CORP (JP)
International Classes:
A61K31/23; A61K9/10; A61K47/14; A61K47/26; A61K47/44; A61P27/04
Domestic Patent References:
| WO2013008714A1 | 2013-01-17 | |||
| WO2011001951A1 | 2011-01-06 |
Foreign References:
| JP2012144527A | 2012-08-02 | |||
| JP2008273959A | 2008-11-13 | |||
| JP2012528876A | 2012-11-15 |
Attorney, Agent or Firm:
PATENT PROFESSIONAL CORPORATION EI-MEI PATENT OFFICE (JP)
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