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Title:
OPHTHALMIC COMPOSITIONS COMPRISING BRINZOLAMIDE
Document Type and Number:
WIPO Patent Application WO/2012/053011
Kind Code:
A3
Abstract:
Disclosed herein is a novel process for preparation of ophthalmic suspensions of Carbonic anhydrase inhibitor such as Brinzolamide. Said process is characterized in that it does not involve autoclaving of the active ingredient Brinzolamide. The invention further discloses ophthalmic suspensions comprising Brinzolamide and combination of Brinzolamide and beta-blocker prepared by the novel process.

Inventors:
OMRAY ASHOK (IN)
CHOUDHARY VARSHA SHASHANK (IN)
BHIDE YOGESH SHARAD (IN)
PARSAI DINESH YASHAWANT (IN)
Application Number:
PCT/IN2011/000720
Publication Date:
October 04, 2012
Filing Date:
October 18, 2011
Export Citation:
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Assignee:
USV LTD (IN)
OMRAY ASHOK (IN)
CHOUDHARY VARSHA SHASHANK (IN)
BHIDE YOGESH SHARAD (IN)
PARSAI DINESH YASHAWANT (IN)
International Classes:
A61K9/08; A61K9/00; A61K31/542
Domestic Patent References:
WO2010103115A12010-09-16
Foreign References:
EP1985618A12008-10-29
JP2010037327A2010-02-18
Other References:
RAJESH M. PATEL *: "PARENTERAL SUSPENSION: AN OVERVIEW", INTERNATIONAL JOURNAL OF CURRENT PHARMACEUTICAL RESEARCH, vol. 2, no. 3, 1 January 2010 (2010-01-01), pages 4 - 13, XP055031426, ISSN: 0975-7066, Retrieved from the Internet
"GUIDE TO INSPECTIONS OF STERILE DRUG SUBSTANCE MANUFACTURERS", 30 April 2009 (2009-04-30), XP002679029, Retrieved from the Internet [retrieved on 20120629]
AKRAM MUHAMMAD ET AL: "Development of new ophthalmic suspension prednisolone acetate 1%.", PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 23, no. 2, April 2010 (2010-04-01), pages 149 - 154, XP002679030, ISSN: 1011-601X
ANONYMOUS: "Australian Public Assessment Report for Brinzolamide/ Timolol Maleate", February 2010 (2010-02-01), pages 1 - 47, XP002679031, Retrieved from the Internet [retrieved on 20120702]
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