Title:
OPHTHALMIC PHARMACEUTICAL PRODUCT
Document Type and Number:
WIPO Patent Application WO/2017/217450
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an ophthalmic pharmaceutical product which, while an ophthalmic solution containing brimonidine and/or a salt thereof, brinzolamide and/or a salt thereof, a carboxyvinyl polymer, and a dihydric alcohol and/or a trihydric alcohol is stored in a storing body that allows visual recognition of the inside thereof, enables suppression of increase in the viscosity of the ophthalmic solution due to exposure thereof to light. According to the present invention, an ophthalmic solution containing brimonidine and/or a salt thereof, brinzolamide and/or a salt thereof, a carboxyvinyl polymer, and a dihydric alcohol and/or a trihydric alcohol is stored in a transparent storing body in which the maximum transmittance of light having a wavelength of 360-460 nm is not higher than 67% and in which the maximum transmittance of light having a wavelength of 600-680 nm is not higher than 78%, whereby, while an insoluble foreign matter test and visual recognition of the amount of a residual liquid are enabled, increase in the viscosity due to exposure to light can be suppressed, thereby ensuring formulation stability.
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Inventors:
IWATSUKA KINYA (JP)
Application Number:
PCT/JP2017/021939
Publication Date:
December 21, 2017
Filing Date:
June 14, 2017
Export Citation:
Assignee:
SENJU PHARMA CO (JP)
International Classes:
A61K31/498; A61K9/08; A61K31/542; A61K47/10; A61K47/32; A61P27/06
Foreign References:
| JP2012530712A | 2012-12-06 | |||
| US6316441B1 | 2001-11-13 | |||
| JP2014055028A | 2014-03-27 |
Attorney, Agent or Firm:
TANAKA, Junya et al. (JP)
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