Title:
OPHTHALMIC PREPARATION FOR TREATING MACULAR EDEMA, OPTIC NEURITIS AND NON-INFECTIOUS ENDOPHTHALMITIS THROUGH EYE DROP ADMINISTRATION
Document Type and Number:
WIPO Patent Application WO/2022/156373
Kind Code:
A1
Abstract:
An ophthalmic preparation for treating macular edema, optic neuritis and non-infectious endophthalmitis. The ophthalmic preparation is a preparation composed of an active ingredient for treating eye diseases and an ophthalmic preparation carrier or auxiliary material; the active ingredient for treating eye diseases is a glucocorticoid medicine and/or a non-steroidal medicine; the ophthalmic preparation carrier or auxiliary material comprises the following ingredients: a surfactant, an ionic polymer and a solvent, or the ophthalmic preparation carrier or auxiliary material contains the following ingredients: povidone with low polymerization degree, povidone with moderate polymerization degree and a solvent. The ophthalmic preparation can carry (wrap) the glucocorticoid and/or the non-steroidal medicines to penetrate through the anterior segment of eyes and be conveyed to the posterior segment of eyes to treat the macular edema, the optic neuritis and the non-infectious endophthalmitis in an eye drop administration mode, and the ophthalmic preparation has extremely excellent clinical use value and positive social significance.
Inventors:
DONG QING (CN)
ZHANG SHU (CN)
CHENG XUAN (CN)
XUE LUBING (CN)
ZHANG SHU (CN)
CHENG XUAN (CN)
XUE LUBING (CN)
Application Number:
PCT/CN2021/134151
Publication Date:
July 28, 2022
Filing Date:
November 29, 2021
Export Citation:
Assignee:
CHENGDU RUIMU BIOMEDICAL TECH CO LTD (CN)
International Classes:
A61K9/08; A61K9/66; A61K31/405; A61K31/573; A61K47/10; A61K47/26; A61K47/36; A61K47/38; A61K47/58; A61P27/02; A61P27/10
Foreign References:
| CN104884049A | 2015-09-02 | |||
| US5929115A | 1999-07-27 | |||
| US20070116777A1 | 2007-05-24 | |||
| CN102085203A | 2011-06-08 | |||
| US20050196370A1 | 2005-09-08 | |||
| US20180263916A1 | 2018-09-20 | |||
| CN110664757A | 2020-01-10 |
Other References:
SUN GANG,YUE LI-QUN,WANG CHEN-XIA: "Relieve the Irritation of Diclofenac Sodium Eye Drops", JOURNAL OF PHARMACEUTICAL RESEARCH, vol. 32, no. 1, 15 January 2013 (2013-01-15), pages 34 - 35, XP055952040, ISSN: 2095-5375, DOI: 10.13506/j.cnki.jpr.2013.01.019
MAO SHIRUI; YANG HONGTU; CHEN JIANMING; BI DIANZHOU: "Uses of Povidone in Pharmaceutics", JOURNAL OF SHENYANG PHARMACEUTICAL UNIVERSITY, vol. 14, no. 3, 20 July 1997 (1997-07-20), XP055952034
URIAS ET AL., VISION RESEARCH, vol. V139, 2017, pages 221 - 227
MANDAL ET AL.: "Ocular delivery of proteins and peptides: Challenges and novel formulation approaches", ADVANCED DRUG DELIVERY REVIEWS, vol. 126, 2018, pages 67 - 95
PEI-XUE LING: "Ophthalmic Drugs and Preparation Technique", 2010, CHINA LIGHT INDUSTRY PRESS, pages: 3
WANG ET AL., MEDIATORS OF INFLAMMATION, vol. 2013
LUACES-RODRIGUEZ ET AL., PHARMACEUTICS, vol. 10, 2018, pages 66
M. HATA ET AL., RETINA, vol. 37, 2017, pages 1320 - 1328
MAO SHIRUI; YANG HONGTU; CHEN JIANMING; BI DIANZHOU: "Uses of Povidone in Pharmaceutics", JOURNAL OF SHENYANG PHARMACEUTICAL UNIVERSITY, vol. 14, no. 3, 20 July 1997 (1997-07-20), XP055952034
URIAS ET AL., VISION RESEARCH, vol. V139, 2017, pages 221 - 227
MANDAL ET AL.: "Ocular delivery of proteins and peptides: Challenges and novel formulation approaches", ADVANCED DRUG DELIVERY REVIEWS, vol. 126, 2018, pages 67 - 95
PEI-XUE LING: "Ophthalmic Drugs and Preparation Technique", 2010, CHINA LIGHT INDUSTRY PRESS, pages: 3
WANG ET AL., MEDIATORS OF INFLAMMATION, vol. 2013
LUACES-RODRIGUEZ ET AL., PHARMACEUTICS, vol. 10, 2018, pages 66
M. HATA ET AL., RETINA, vol. 37, 2017, pages 1320 - 1328
Attorney, Agent or Firm:
GAOYUNG INTELLECTUAL PROPERTY AGENCY (GENERAL PARTNERSHIP) (CN)
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